PDB entry 4dqf

View 4dqf on RCSB PDB site
Description: Crystal Structure of (G16A/L38A) HIV-1 Protease in Complex with DRV
Class: hydrolase/hydrolase inhibitor
Keywords: HIV-1 protease, drug resistance, drug design, Protease inhibitors, AIDS, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2012-02-15, released 2012-03-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aspartyl protease
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • PDB 4DQF (0-98)
    Domains in SCOPe 2.07: d4dqfa_
  • Chain 'B':
    Compound: Aspartyl protease
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • PDB 4DQF (0-98)
    Domains in SCOPe 2.07: d4dqfb_
  • Heterogens: 017, SO4, EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4dqfA (A:)
    pqitlwkrplvtiriagqlkealldtgaddtvieemnapgkwkpkmiggiggfikvrqyd
    qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf
    

    Sequence, based on observed residues (ATOM records): (download)
    >4dqfA (A:)
    pqitlwkrplvtiriagqlkealldtgaddtvieeapgkwkpkmiggiggfikvrqydqi
    iieiaghkaigtvlvgptpvniigrnlltqigatlnf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4dqfB (B:)
    pqitlwkrplvtiriagqlkealldtgaddtvieemnapgkwkpkmiggiggfikvrqyd
    qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf