PDB entry 4dit

View 4dit on RCSB PDB site
Description: Crystal Structure of GSK3beta in complex with a Imidazopyridine inhibitor
Class: transferase/transferase inhibitor
Keywords: kinase, Y216 Phosphorylation, PHOSPHOTRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-01-31, released 2012-02-15
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-02-29, with a file datestamp of 2012-02-24.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.24
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4dita_
  • Heterogens: 0KD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ditA (A:)
mrgskvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelv
aikkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrv
arhysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfg
sakqlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsg
vdqlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlle
ytptarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilippha
riqaaastptnaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4ditA (A:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssdevylnlvldyvpetvyrvarhysrakqtlpviyv
klymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyyy
rapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqir
emwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpa
lfnfttqelssnpplatilipphariqaa