PDB entry 4cym

View 4cym on RCSB PDB site
Description: Complex of human VARP-ANKRD1 with Rab32-GppCp
Class: transport protein
Keywords: transport protein, varp, rab-effector, rab, endosome, vesicle trafficking, melanosome biogenesis
Deposited on 2014-04-13, released 2014-06-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-06-25, with a file datestamp of 2014-06-20.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.19466
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ras-related protein rab-32
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13637
      • engineered mutation (89)
    Domains in SCOPe 2.08: d4cyma_
  • Chain 'B':
    Compound: ras-related protein rab-32
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13637
      • engineered mutation (89)
    Domains in SCOPe 2.08: d4cymb_
  • Chain 'C':
    Compound: ras-related protein rab-32
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13637
      • engineered mutation (89)
    Domains in SCOPe 2.08: d4cymc_
  • Chain 'D':
    Compound: ankyrin repeat domain-containing protein 27
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: ankyrin repeat domain-containing protein 27
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: ankyrin repeat domain-containing protein 27
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GCP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cymA (A:)
gplgsmagggagdpglgaaaapapetrehlfkvlvigelgvgktsiikryvhqlfsqhyr
atigvdfalkvlnwdsrtlvrlqlwdiaglerfgnmtrvyykeavgafvvfdisrsstfe
avlkwksdldskvhlpngspipavllankcdqnkdssqspsqvdqfckehgfagwfetsa
kdninieeaarflvekilvnhqsfpneendvdkikldqetlraenksqcc

    Sequence, based on observed residues (ATOM records): (download) 
    >4cymA (A:)
rehlfkvlvigelgvgktsiikryvhqlfsqhyratigvdfalkvlnwdsrtlvrlqlwd
iaglerfgnmtrvyykeavgafvvfdisrsstfeavlkwksdldskvhlpngspipavll
ankcdqnkdssqspsqvdqfckehgfagwfetsakdninieeaarflvekilvnhqs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4cymB (B:)
gplgsmagggagdpglgaaaapapetrehlfkvlvigelgvgktsiikryvhqlfsqhyr
atigvdfalkvlnwdsrtlvrlqlwdiaglerfgnmtrvyykeavgafvvfdisrsstfe
avlkwksdldskvhlpngspipavllankcdqnkdssqspsqvdqfckehgfagwfetsa
kdninieeaarflvekilvnhqsfpneendvdkikldqetlraenksqcc

    Sequence, based on observed residues (ATOM records): (download) 
    >4cymB (B:)
ehlfkvlvigelgvgktsiikryvhqlfsqhyratigvdfalkvlnwdsrtlvrlqlwdi
aglerfgnmtrvyykeavgafvvfdisrsstfeavlkwksdldskvhlpngspipavlla
nkcdqnkdssqspsqvdqfckehgfagwfetsakdninieeaarflvekilvnhq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4cymC (C:)
gplgsmagggagdpglgaaaapapetrehlfkvlvigelgvgktsiikryvhqlfsqhyr
atigvdfalkvlnwdsrtlvrlqlwdiaglerfgnmtrvyykeavgafvvfdisrsstfe
avlkwksdldskvhlpngspipavllankcdqnkdssqspsqvdqfckehgfagwfetsa
kdninieeaarflvekilvnhqsfpneendvdkikldqetlraenksqcc

    Sequence, based on observed residues (ATOM records): (download) 
    >4cymC (C:)
rehlfkvlvigelgvgktsiikryvhqlfsqhyratigvdfalkvlnwdsrtlvrlqlwd
iaglerfgnmtrvyykeavgafvvfdisrsstfeavlkwksdldskvhlpngspipavll
ankcdqnkdssqspsqvdqfckehgfagwfetsakdninieeaarflvekilvnhqs

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.