PDB entry 4cp3
View 4cp3 on RCSB PDB site
Description: The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin.
Class: immune system
Keywords: immune system, btb/poz, transcriptional repressor, rifamycin, antibiotic, smrt, inhibitor
Deposited on
2014-01-31, released
2014-03-19
The last revision prior to the SCOPe 2.08 freeze date was dated
2014-03-19, with a file datestamp of
2014-03-14.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.20193
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: B-cell lymphoma 6 protein
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P41182 (4-End)
- expression tag (1-3)
- engineered mutation (62)
- engineered mutation (79)
Domains in SCOPe 2.08: d4cp3a1, d4cp3a2 - Chain 'B':
Compound: B-cell lymphoma 6 protein
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P41182 (4-123)
- expression tag (2-3)
- engineered mutation (62)
- engineered mutation (79)
Domains in SCOPe 2.08: d4cp3b1, d4cp3b2 - Heterogens: RBT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4cp3A (A:)
gasqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikas
Sequence, based on observed residues (ATOM records): (download)
>4cp3A (A:)
asqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdql
krnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfi
ka
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4cp3B (B:)
gasqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikas
Sequence, based on observed residues (ATOM records): (download)
>4cp3B (B:)
sqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlk
rnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as