PDB entry 4cnx

View 4cnx on RCSB PDB site
Description: Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion CO2 capture
Class: lyase
Keywords: lyase, protein engineering, co2 capture
Deposited on 2014-01-25, released 2015-02-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-01-13, with a file datestamp of 2016-01-08.
Experiment type: XRAY
Resolution: 1.23 Å
R-factor: N/A
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00921 (Start-261)
      • engineered mutation (9)
      • engineered mutation (19)
      • engineered mutation (25)
      • engineered mutation (37)
      • engineered mutation (40)
      • engineered mutation (51)
      • engineered mutation (58)
      • engineered mutation (63)
      • engineered mutation (75)
      • engineered mutation (86)
      • engineered mutation (137)
      • engineered mutation (170)
      • engineered mutation (178)
      • engineered mutation (187)
      • engineered mutation (221)
      • engineered mutation (239)
      • engineered mutation (253)
      • engineered mutation (255)
    Domains in SCOPe 2.06: d4cnxa_
  • Heterogens: ZN, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4cnxA (A:)
    mgmshhwgydkhngpehwhedfpiadgerqspvdidtdavdqdpalkplaldygeatsdr
    mvndghsfnveyddsedkavlkdgpldgtyrlvqfhfhwgssddqgsehtvdrkkyaael
    hlvhwntkygdfgtaaqepdglavvgvflkvgdanpalqkvldaldsiktegkstdfpdf
    dpgsllpevldywtypgslttppllesvtwivlkepisvsseqmlkfrtlnfnaegepee
    lmlanwrpaqplkdrevrgfpk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4cnxA (A:)
    hwgydkhngpehwhedfpiadgerqspvdidtdavdqdpalkplaldygeatsdrmvndg
    hsfnveyddsedkavlkdgpldgtyrlvqfhfhwgssddqgsehtvdrkkyaaelhlvhw
    ntkygdfgtaaqepdglavvgvflkvgdanpalqkvldaldsiktegkstdfpdfdpgsl
    lpevldywtypgslttppllesvtwivlkepisvsseqmlkfrtlnfnaegepeelmlan
    wrpaqplkdrevrgfpk