PDB entry 4cc4

View 4cc4 on RCSB PDB site
Description: Complex of InlC of Listeria monocytogenes and human Tuba C-terminal SH3 domain
Class: cell invasion
Keywords: cell invasion, bacterial infection, pathogenesis, listerial cell-cell spread, virulence factor, protein-protein interactions, leucine-rich repeat, src homology 3 domain, disruption of cortical tension, cell membrane protrusions
Deposited on 2013-10-17, released 2013-10-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-05, with a file datestamp of 2017-06-30.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inlc protein
    Species: LISTERIA MONOCYTOGENES EGD-E [TaxId:169963]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P71451 (2-264)
      • expression tag (0-1)
      • engineered mutation (213-214)
    Domains in SCOPe 2.08: d4cc4a1, d4cc4a2, d4cc4a3
  • Chain 'B':
    Compound: Dynamin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XZF7 (2-66)
      • expression tag (0-1)
      • expression tag (67)
    Domains in SCOPe 2.08: d4cc4b1, d4cc4b2, d4cc4b3
  • Chain 'C':
    Compound: inlc protein
    Species: LISTERIA MONOCYTOGENES EGD-E [TaxId:169963]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P71451 (2-264)
      • expression tag (1)
      • engineered mutation (213-214)
      • expression tag (265)
    Domains in SCOPe 2.08: d4cc4c1, d4cc4c2, d4cc4c3, d4cc4c4
  • Chain 'D':
    Compound: Dynamin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XZF7 (Start-66)
      • expression tag (67)
    Domains in SCOPe 2.08: d4cc4d1, d4cc4d2
  • Chain 'E':
    Compound: inlc protein
    Species: LISTERIA MONOCYTOGENES EGD-E [TaxId:169963]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P71451 (2-264)
      • engineered mutation (213-214)
    Domains in SCOPe 2.08: d4cc4e1, d4cc4e2
  • Chain 'F':
    Compound: Dynamin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XZF7 (2-66)
      • expression tag (0-1)
      • expression tag (67)
    Domains in SCOPe 2.08: d4cc4f1, d4cc4f2, d4cc4f3
  • Heterogens: GOL, CL, PE4, SO4, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cc4A (A:)
asesiqrptpinqvfpdpglanavkqnlgkqsvtdlvsqkelsgvqnfngdnsniqslag
mqfftnlkelhlshnqisdlsplkdltkleelsvnrnrlknlngipsaclsrlfldnnel
rdtdslihlknleilsirnnklksivmlgflsklevldlhgneitntggltrlkkvnwid
ltgqkcvnepvkyqpelyitntvkdpdgrwispaaisnggsyvdgcvlwelpvytdevsy
kfseyinvgeteaifdgtvtqpiknk

    Sequence, based on observed residues (ATOM records): (download) 
    >4cc4A (A:)
asesiqrptpinqvfpdpglanavkqnlgkqsvtdlvsqkelsgvqnfngdnsniqslag
mqfftnlkelhlshnqisdlsplkdltkleelsvnrnrlknlngipsaclsrlfldnnel
rdtdslihlknleilsirnnklksivmlgflsklevldlhgneitntggltrlkkvnwid
ltgqkcvnepvkyqpelyitntvkdpdgrwispaaisnggsyvdgcvlwelpvytdevsy
kfseyinvgeteaifdgtvtqpikn

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4cc4B (B:)
gpegnqvyfavytfkarnpnelsvsanqklkilefkdvtgntewwlaevngkkgyvpsny
irkteyta

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4cc4C (C:)
asesiqrptpinqvfpdpglanavkqnlgkqsvtdlvsqkelsgvqnfngdnsniqslag
mqfftnlkelhlshnqisdlsplkdltkleelsvnrnrlknlngipsaclsrlfldnnel
rdtdslihlknleilsirnnklksivmlgflsklevldlhgneitntggltrlkkvnwid
ltgqkcvnepvkyqpelyitntvkdpdgrwispaaisnggsyvdgcvlwelpvytdevsy
kfseyinvgeteaifdgtvtqpiknk

    Sequence, based on observed residues (ATOM records): (download) 
    >4cc4C (C:)
sesiqrptpinqvfpdpglanavkqnlgkqsvtdlvsqkelsgvqnfngdnsniqslagm
qfftnlkelhlshnqisdlsplkdltkleelsvnrnrlknlngipsaclsrlfldnnelr
dtdslihlknleilsirnnklksivmlgflsklevldlhgneitntggltrlkkvnwidl
tgqkcvnepvkyqpelyitntvkdpdgrwispaaisnggsyvdgcvlwelpvytdevsyk
fseyinvgeteaifdgtvtqpiknk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4cc4D (D:)
gpegnqvyfavytfkarnpnelsvsanqklkilefkdvtgntewwlaevngkkgyvpsny
irkteyta

    Sequence, based on observed residues (ATOM records): (download) 
    >4cc4D (D:)
nqvyfavytfkarnpnelsvsanqklkilefkdvtgntewwlaevngkkgyvpsnyirkt
eyta

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4cc4E (E:)
asesiqrptpinqvfpdpglanavkqnlgkqsvtdlvsqkelsgvqnfngdnsniqslag
mqfftnlkelhlshnqisdlsplkdltkleelsvnrnrlknlngipsaclsrlfldnnel
rdtdslihlknleilsirnnklksivmlgflsklevldlhgneitntggltrlkkvnwid
ltgqkcvnepvkyqpelyitntvkdpdgrwispaaisnggsyvdgcvlwelpvytdevsy
kfseyinvgeteaifdgtvtqpiknk

    Sequence, based on observed residues (ATOM records): (download) 
    >4cc4E (E:)
esiqrptpinqvfpdpglanavkqnlgkqsvtdlvsqkelsgvqnfngdnsniqslagmq
fftnlkelhlshnqisdlsplkdltkleelsvnrnrlknlngipsaclsrlfldnnelrd
tdslihlknleilsirnnklksivmlgflsklevldlhgneitntggltrlkkvnwidlt
gqkcvnepvkyqpelyitntvkdpdgrwispaaisnggsyvdgcvlwelpvytdevsykf
seyinvgeteaifdgtvtqpikn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4cc4F (F:)
gpegnqvyfavytfkarnpnelsvsanqklkilefkdvtgntewwlaevngkkgyvpsny
irkteyta