PDB entry 4cad

View 4cad on RCSB PDB site
Description: Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1
Class: protein binding
Keywords: protein binding, integral membrane protease, monoclonal antibody fab fragment
Deposited on 2013-10-08, released 2013-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antibody fab fragment light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD
    Domains in SCOPe 2.08: d4cada1, d4cada2
  • Chain 'B':
    Compound: antibody fab fragment heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD
    Domains in SCOPe 2.08: d4cadb_
  • Chain 'C':
    Compound: ras and a-factor converting enzyme 1, rce1
    Species: Methanococcus maripaludis [TaxId:39152]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: antibody fab fragment light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD
    Domains in SCOPe 2.08: d4cadd1, d4cadd2
  • Chain 'E':
    Compound: antibody fab fragment heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD
    Domains in SCOPe 2.08: d4cade_
  • Chain 'F':
    Compound: ras and a-factor converting enzyme 1, rce1
    Species: Methanococcus maripaludis [TaxId:39152]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: antibody fab fragment light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD (0-End)
    Domains in SCOPe 2.08: d4cadg1, d4cadg2
  • Chain 'H':
    Compound: antibody fab fragment heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD (0-End)
    Domains in SCOPe 2.08: d4cadh_
  • Chain 'I':
    Compound: ras and a-factor converting enzyme 1, rce1
    Species: Methanococcus maripaludis [TaxId:39152]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: antibody fab fragment light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD (0-End)
    Domains in SCOPe 2.08: d4cadj1, d4cadj2
  • Chain 'K':
    Compound: antibody fab fragment heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4CAD (0-End)
    Domains in SCOPe 2.08: d4cadk_
  • Chain 'L':
    Compound: ras and a-factor converting enzyme 1, rce1
    Species: Methanococcus maripaludis [TaxId:39152]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BOG, LMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cadA (A:)
diqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvps
rfsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadA (A:)
iqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvpsr
fsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4cadB (B:)
qvqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntny
nekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgts
vtvssakttppsdyplapvcgdtsgssvtlgclvkgyfpepvtltwnsgslssgvhtfpa
vlqsdlytlsssvtvtsstwpsqsitcnvahpasstkvdkkieprgp

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadB (B:)
vqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntnyn
ekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgtsv
tvssakttppsdyplapvcggssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqs
dlytlsssvtvtsstwpsqsitcnvahpasstkvdkkiepr

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4cadD (D:)
diqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvps
rfsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadD (D:)
iqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvpsr
fsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrn

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4cadE (E:)
qvqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntny
nekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgts
vtvssakttppsdyplapvcgdtsgssvtlgclvkgyfpepvtltwnsgslssgvhtfpa
vlqsdlytlsssvtvtsstwpsqsitcnvahpasstkvdkkieprgp

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadE (E:)
vqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntnyn
ekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgtsv
tvssakttppsdyplapvcgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsd
lytlsssvtvtsstwpsqsitcnvahpasstkvdkkiepr

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4cadG (G:)
diqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvps
rfsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadG (G:)
diqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvps
rfsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4cadH (H:)
qvqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntny
nekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgts
vtvssakttppsdyplapvcgdtsgssvtlgclvkgyfpepvtltwnsgslssgvhtfpa
vlqsdlytlsssvtvtsstwpsqsitcnvahpasstkvdkkieprgp

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadH (H:)
qvqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntny
nekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgts
vtvssakttppsdyplapvcgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqs
dlytlsssvtvtsstwpsqsitcnvahpasstkvdkkiepr

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >4cadJ (J:)
diqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvps
rfsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadJ (J:)
diqltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvynaktladgvps
rfsgsgsgtqyslkinslqpedfgnyycqhfwstpwtfgggtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >4cadK (K:)
qvqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntny
nekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgts
vtvssakttppsdyplapvcgdtsgssvtlgclvkgyfpepvtltwnsgslssgvhtfpa
vlqsdlytlsssvtvtsstwpsqsitcnvahpasstkvdkkieprgp

    Sequence, based on observed residues (ATOM records): (download) 
    >4cadK (K:)
qvqlkqsgaelmkpgasvkisckatgykfssywiewvkqrpghglewigeifpgsgntny
nekfkgkatltadtssntaymqlssltsedsavyycarrgafysygssyyamdfwgqgts
vtvssakttppsdyplapvcgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqs
dlytlsssvtvtsstwpsqsitcnvahpasstkvdkkiepr

  • Chain 'L':
    No sequence available.