PDB entry 4c7b

View 4c7b on RCSB PDB site
Description: Complex of human Sirt3 with Bromo-Resveratrol and Fluor-De-Lys peptide
Class: hydrolase/peptide
Keywords: hydrolase-peptide complex, hydrolase, sirtuin, inhibitor, activation, resveratrol, sirt1, metabolic sensor, metabolism, aging
Deposited on 2013-09-20, released 2013-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-12-14, with a file datestamp of 2016-12-09.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c7ba_
  • Chain 'B':
    Compound: peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 4C7B (0-3)
  • Heterogens: ZN, BVB, IPA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4c7bA (A:)
    ssdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpyp
    eaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglerv
    sgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffge
    plpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhpr
    srdvaqlgdvvhgveslvellgwteemrdlvqretgkldgpdk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c7bA (A:)
    klslqdvaeliraracqrvvvmvgagistpsgipdfrqydlpypeaifelpfffhnpkpf
    ftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgipasklveahgtfa
    satctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpqrfllhvvdfpma
    dlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdvaqlgdvvhgves
    lvellgwteemrdlvqretgk
    

  • Chain 'B':
    No sequence available.