PDB entry 4c51

View 4c51 on RCSB PDB site
Description: Crystal Structure of the Catalase-Peroxidase (KatG) R418L mutant from Mycobacterium Tuberculosis
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2013-09-10, released 2013-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Catalase-peroxidase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08129 (Start-739)
      • engineered mutation (417)
    Domains in SCOPe 2.08: d4c51a1, d4c51a2
  • Chain 'B':
    Compound: Catalase-peroxidase
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08129 (Start-739)
      • engineered mutation (417)
    Domains in SCOPe 2.08: d4c51b1, d4c51b2
  • Heterogens: HEM, GLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c51A (A:)
mpeqhppitetttgaasngcpvvghmkypvegggnqdwwpnrlnlkvlhqnpavadpmga
afdyaaevatidvdaltrdieevmttsqpwwpadyghygplfirmawhaagtyrihdgrg
gagggmqrfaplnswpdnasldkarrllwpvkkkygkklswadlivfagncalesmgfkt
fgfgfgrvdqwepdevywgkeatwlgderysgkrdlenplaavqmgliyvnpegpngnpd
pmaaavdiretfrrmamndvetaalivgghtfgkthgagpadlvgpepeaapleqmglgw
kssygtgtgkdaitsgievvwtntptkwdnsfleilygyeweltkspagawqytakdgag
agtipdpfggpgrsptmlatdlslrvdpiyeritrrwlehpeeladefakawyklihldm
gpvarylgplvpkqtllwqdpvpavshdlvgeaeiaslksqirasgltvsqlvstawaaa
ssfrgsdkrgganggrirlqpqvgwevndpdgdlrkvirtleeiqesfnsaapgnikvsf
adlvvlggcaaiekaakaaghnitvpftpgrtdasqeqtdvesfavlepkadgfrnylgk
gnplpaeymlldkanlltlsapemtvlvgglrvlganykrlplgvfteasesltndffvn
lldmgitwepspaddgtyqgkdgsgkvkwtgsrvdlvfgsnselralvevygaddaqpkf
vqdfvaawdkvmnldrfdvr

    Sequence, based on observed residues (ATOM records): (download) 
    >4c51A (A:)
ghmkypvegggnqdwwpnrlnlkvlhqnpavadpmgaafdyaaevatidvdaltrdieev
mttsqpwwpadyghygplfirmawhaagtyrihdgrggagggmqrfaplnswpdnasldk
arrllwpvkkkygkklswadlivfagncalesmgfktfgfgfgrvdqwepdevywgkeat
wlgderysgkrdlenplaavqmgliyvnpegpngnpdpmaaavdiretfrrmamndveta
alivgghtfgkthgagpadlvgpepeaapleqmglgwkssygtgtgkdaitsgievvwtn
tptkwdnsfleilygyeweltkspagawqytakdgagagtipdpfggpgrsptmlatdls
lrvdpiyeritrrwlehpeeladefakawyklihldmgpvarylgplvpkqtllwqdpvp
avshdlvgeaeiaslksqirasgltvsqlvstawaaassfrgsdkrgganggrirlqpqv
gwevndpdgdlrkvirtleeiqesfnsaapgnikvsfadlvvlggcaaiekaakaaghni
tvpftpgrtdasqeqtdvesfavlepkadgfrnylgkgnplpaeymlldkanlltlsape
mtvlvgglrvlganykrlplgvfteasesltndffvnlldmgitwepspaddgtyqgkdg
sgkvkwtgsrvdlvfgsnselralvevygaddaqpkfvqdfvaawdkvmnldrfdvr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4c51B (B:)
mpeqhppitetttgaasngcpvvghmkypvegggnqdwwpnrlnlkvlhqnpavadpmga
afdyaaevatidvdaltrdieevmttsqpwwpadyghygplfirmawhaagtyrihdgrg
gagggmqrfaplnswpdnasldkarrllwpvkkkygkklswadlivfagncalesmgfkt
fgfgfgrvdqwepdevywgkeatwlgderysgkrdlenplaavqmgliyvnpegpngnpd
pmaaavdiretfrrmamndvetaalivgghtfgkthgagpadlvgpepeaapleqmglgw
kssygtgtgkdaitsgievvwtntptkwdnsfleilygyeweltkspagawqytakdgag
agtipdpfggpgrsptmlatdlslrvdpiyeritrrwlehpeeladefakawyklihldm
gpvarylgplvpkqtllwqdpvpavshdlvgeaeiaslksqirasgltvsqlvstawaaa
ssfrgsdkrgganggrirlqpqvgwevndpdgdlrkvirtleeiqesfnsaapgnikvsf
adlvvlggcaaiekaakaaghnitvpftpgrtdasqeqtdvesfavlepkadgfrnylgk
gnplpaeymlldkanlltlsapemtvlvgglrvlganykrlplgvfteasesltndffvn
lldmgitwepspaddgtyqgkdgsgkvkwtgsrvdlvfgsnselralvevygaddaqpkf
vqdfvaawdkvmnldrfdvr

    Sequence, based on observed residues (ATOM records): (download) 
    >4c51B (B:)
ghmkypvegggnqdwwpnrlnlkvlhqnpavadpmgaafdyaaevatidvdaltrdieev
mttsqpwwpadyghygplfirmawhaagtyrihdgrggagggmqrfaplnswpdnasldk
arrllwpvkkkygkklswadlivfagncalesmgfktfgfgfgrvdqwepdevywgkeat
wlgderysgkrdlenplaavqmgliyvnpegpngnpdpmaaavdiretfrrmamndveta
alivgghtfgkthgagpadlvgpepeaapleqmglgwkssygtgtgkdaitsgievvwtn
tptkwdnsfleilygyeweltkspagawqytakdgagagtipdpfggpgrsptmlatdls
lrvdpiyeritrrwlehpeeladefakawyklihldmgpvarylgplvpkqtllwqdpvp
avshdlvgeaeiaslksqirasgltvsqlvstawaaassfrgsdkrgganggrirlqpqv
gwevndpdgdlrkvirtleeiqesfnsaapgnikvsfadlvvlggcaaiekaakaaghni
tvpftpgrtdasqeqtdvesfavlepkadgfrnylgkgnplpaeymlldkanlltlsape
mtvlvgglrvlganykrlplgvfteasesltndffvnlldmgitwepspaddgtyqgkdg
sgkvkwtgsrvdlvfgsnselralvevygaddaqpkfvqdfvaawdkvmnldrfdvr