PDB entry 4c2v
View 4c2v on RCSB PDB site
Description: Aurora B kinase in complex with the specific inhibitor Barasertib
Class: transferase/cell cycle
Keywords: transferase-cell cycle complex, azd1152
Deposited on
2013-08-20, released
2014-02-26
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-03-19, with a file datestamp of
2014-03-14.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: 0.16817
AEROSPACI score: 0.57
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: aurora kinase b-a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4c2va_ - Chain 'B':
Compound: aurora kinase b-a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4c2vb_ - Chain 'C':
Compound: inner centromere protein a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: inner centromere protein a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
- Heterogens: YJA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4c2vA (A:)
qntalaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegve
hqlrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsat
fmeeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldy
lppemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdg
skdliskllryhppqrlplkgvmehpwvkansrrvlppvyqstqs
Sequence, based on observed residues (ATOM records): (download)
>4c2vA (A:)
kftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehqlrreieiqs
hlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeeladalhy
cherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylppemiegkth
dekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdliskllry
hppqrlplkgvmehpwvkansrrvlppvyqs
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4c2vB (B:)
qntalaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegve
hqlrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsat
fmeeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldy
lppemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdg
skdliskllryhppqrlplkgvmehpwvkansrrvlppvyqstqs
Sequence, based on observed residues (ATOM records): (download)
>4c2vB (B:)
qntalaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegve
hqlrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsat
fmeeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldy
lppemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdg
skdliskllryhppqrlplkgvmehpwvkansrrvlppvyq
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.