PDB entry 4bw1

View 4bw1 on RCSB PDB site
Description: The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand
Class: transcription
Keywords: transcription, inhibitor, histone, epigenetic reader, antagonist
Deposited on 2013-06-29, released 2013-09-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-03-19, with a file datestamp of 2014-03-14.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.19008
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-126)
    • expression tag (0-1)
  Domains in SCOPe 2.07: d4bw1a1, d4bw1a2
• Heterogens: EDO, S5B, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4bw1A (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee