PDB entry 4bv3

View 4bv3 on RCSB PDB site
Description: crystal structure of sirt3 in complex with the inhibitor ex-527 and nad
Class: hydrolase
Keywords: hydrolase, inhibitor
Deposited on 2013-06-24, released 2013-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-08-07, with a file datestamp of 2013-08-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.16544
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4bv3a_
  • Heterogens: NAD, APR, OCZ, ZN, NO3, GOL, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bv3A (A:)
gssdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpy
peaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgler
vsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffg
eplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhp
rsrdvaqlgdvvhgveslvellgwteemrdlvqretgkldgpdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4bv3A (A:)
klslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaife
lpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgipa
sklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpqr
fllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdva
qlgdvvhgveslvellgwteemrdlvqret