PDB entry 4bn1

View 4bn1 on RCSB PDB site
Description: Crystal structure of V174M mutant of Aurora-A kinase
Class: transferase
Keywords: transferase, protein kinase, mitosis
Deposited on 2013-05-13, released 2014-03-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-26, with a file datestamp of 2014-03-21.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.1945
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aurora kinase A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14965
      • engineered mutation (55)
    Domains in SCOPe 2.08: d4bn1a_
  • Heterogens: ADP, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bn1A (A:)
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rreveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyit
elanalsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylpp
emiegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegard
lisrllkhnpsqrpmlrevlehpwitansskpsncqnkesaskqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4bn1A (A:)
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shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppemiegrm
hdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllk
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