PDB entry 4bic

View 4bic on RCSB PDB site
Description: Crystal Structures of Ask1-inhibitor Complexes
Class: transferase
Keywords: transferase
Deposited on 2013-04-10, released 2013-07-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-08-07, with a file datestamp of 2013-08-02.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: 0.2094
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mitogen-activated protein kinase kinase kinase 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99683
      • engineered mutation (178)
    Domains in SCOPe 2.08: d4bica_
  • Chain 'B':
    Compound: mitogen-activated protein kinase kinase kinase 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4bicb_
  • Heterogens: IE4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bicA (A:)
steegdcesdlleydyeydengdrvvlgkgtygivyagrdlsnqvriaikeiperdsrys
qplheeialhkhlkhknivqylgsfsengfikifmeqvpggslsallrskwgplkdneqt
igfytkqileglkylhdnqivhrdikgdnvlintysgvlkisdfgtskrlaginpcteef
tgtlqymapeiidkgprgygkaadiwslgctiiematgkppfyelgepqaamfkvgmfkv
hpeipesmsaeakafilkcfepdpdkracandllvdeflkvsskkkktqpklsalsagsn
eylrsislpvpvlvedts

    Sequence, based on observed residues (ATOM records): (download) 
    >4bicA (A:)
lleydyeydengdrvvlgkgtygivyagrdlsnqvriaikeipesqplheeialhkhlkh
knivqylgsfsengfikifmeqvpggslsallrskwgplkdneqtigfytkqileglkyl
hdnqivhrdikgdnvlintysgvlkisdfgtskrlageftgtlqymapeiidkgprgygk
aadiwslgctiiematgkppfyelgepqaamfkvgmfkvhpeipesmsaeakafilkcfe
pdpdkracandllvdeflkv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bicB (B:)
steegdcesdlleydyeydengdrvvlgkgtygivyagrdlsnqvriaikeiperdsrys
qplheeialhkhlkhknivqylgsfsengfikifmeqvpggslsallrskwgplkdneqt
igfytkqileglkylhdnqivhrdikgdnvlintysgvlkisdfgtskrlaginpcteef
tgtlqymapeiidkgprgygkaadiwslgctiiematgkppfyelgepqaamfkvgmfkv
hpeipesmsaeakafilkcfepdpdkracandllvdeflkvsskkkktqpklsalsagsn
eylrsislpvpvlvedts

    Sequence, based on observed residues (ATOM records): (download) 
    >4bicB (B:)
lleydyeydengdrvvlgkgtygivyagrdlsnqvriaikeipersqplheeialhkhlk
hknivqylgsfsengfikifmeqvpggslsallrskwgplkdneqtigfytkqileglky
lhdnqivhrdikgdnvlintysgvlkisdfgtskrlatgtlqymapeiidkgprgygkaa
diwslgctiiematgkppfyelgepqaamfkvgmfkvhpeipesmsaeakafilkcfepd
pdkracandllvdeflkvs