PDB entry 4bi1

View 4bi1 on RCSB PDB site
Description: Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor
Class: transferase
Keywords: transferase, protein kinase, mitosis
Deposited on 2013-04-09, released 2013-05-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase TTK
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33981 (23-End)
      • expression tag (20-22)
    Domains in SCOPe 2.08: d4bi1a1, d4bi1a2
  • Heterogens: 7PE, ZO6, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bi1A (A:)
mhhhhhhssgvdlgtenlyfqsmsvkgriysilkqigsggsskvfqvlnekkqiyaikyv
nleeadnqtldsyrneiaylnklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkk
kksidpwerksywknmleavhtihqhgivhsdlkpanflivdgmlklidfgianqmqpdt
tsvvkdsqvgtvnymppeaikdmsssrengkskskispksdvwslgcilyymtygktpfq
qiinqisklhaiidpnheiefpdipekdlqdvlkcclkrdpkqrisipellahpyvqiqt
hpvnqmakgttee

    Sequence, based on observed residues (ATOM records): (download) 
    >4bi1A (A:)
qsmsvkgriysilkqigsgsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiayln
klqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmleavh
tihqhgivhsdlkpanflivdgmlklidfgianqvgtvnymppeaikdispksdvwslgc
ilyymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdvlkcclkrdpkqrisi
pellahpyvqiq