PDB entry 4bda

View 4bda on RCSB PDB site
Description: Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2)
Class: transferase
Keywords: transferase
Deposited on 2012-10-05, released 2013-06-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-06-26, with a file datestamp of 2013-06-21.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.183
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase chk2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O96017 (7-End)
      • expression tag (6)
    Domains in SCOPe 2.06: d4bdaa1, d4bdaa2
  • Heterogens: NO3, EDO, VFB, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bdaA (A:)
gplgshmsvypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsar
eadpalnveteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkea
tcklyfyqmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmr
tlcgtptylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqits
gkynfipevwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllsee
nestalpqvlaqpstsrkrpregeaegae

    Sequence, based on observed residues (ATOM records): (download) 
    >4bdaA (A:)
msvypkalrdeyimsktlgsevklaferktckkvaikiisknveteieilkklnhpciik
iknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengiihrd
lkpenvllssqeedclikitdfghskiletslmrtlcgtptylapevlvsvgtagynrav
dcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlvkkllv
vdpkarftteealrhpwlqdedmkrkfqdllseenestalpqvl