PDB entry 4b8w

View 4b8w on RCSB PDB site
Description: Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2012-08-31, released 2012-11-21
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-12-05, with a file datestamp of 2012-11-30.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.2035
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GDP-l-fucose synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13630 (5-318)
      • expression tag (0-4)
    Domains in SCOPe 2.03: d4b8wa_
  • Chain 'B':
    Compound: GDP-l-fucose synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13630 (5-End)
      • expression tag (2-4)
    Domains in SCOPe 2.03: d4b8wb_
  • Heterogens: NAP, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4b8wA (A:)
nlyfqsmrilvtggsglvgkaiqkvvadgaglpgedwvfvsskdadltdtaqtralfekv
qpthvihlaamvgglfrnikynldfwrknvhmndnvlhsafevgarkvvsclstcifpdk
ttypidetmihngpphnsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfn
iedghvlpglihkvhlakssgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepii
lsvgeedevsikeaaeavveamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpf
kqavketcawftdnyeqar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4b8wB (B:)
nlyfqsmrilvtggsglvgkaiqkvvadgaglpgedwvfvsskdadltdtaqtralfekv
qpthvihlaamvgglfrnikynldfwrknvhmndnvlhsafevgarkvvsclstcifpdk
ttypidetmihngpphnsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfn
iedghvlpglihkvhlakssgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepii
lsvgeedevsikeaaeavveamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpf
kqavketcawftdnyeqar

    Sequence, based on observed residues (ATOM records): (download) 
    >4b8wB (B:)
yfqsmrilvtggsglvgkaiqkvvapgedwvfvsskdadltdtaqtralfekvqpthvih
laamvnldfwrknvhmndnvlhsafevgarkvvsclstcifpdkttypidetmihngpph
nsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfniedghvlpglihkvhl
akssgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepiilsvgeedevsikeaae
avveamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpfkqavketcawftdnye