PDB entry 4asi

View 4asi on RCSB PDB site
Description: Crystal structure of human ACACA C-terminal domain
Class: ligase
Keywords: ligase, protein
Deposited on 2012-05-01, released 2012-08-29
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-08-29, with a file datestamp of 2012-08-24.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.20367
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA carboxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asia1, d4asia2
  • Chain 'B':
    Compound: Acetyl-CoA carboxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asib1, d4asib2
  • Chain 'C':
    Compound: Acetyl-CoA carboxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asic1, d4asic2
  • Chain 'D':
    Compound: Acetyl-CoA carboxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asid1, d4asid2
  • Chain 'E':
    Compound: Acetyl-CoA carboxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asie1, d4asie2
  • Chain 'F':
    Compound: Acetyl-CoA carboxylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asif1, d4asif2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4asiA (A:)
smlintpyvtkdllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplps
dmltytelvlddqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrig
sfgpqedllflraselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyr
ylyltpqdykrvsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagessl
ayneiitislvtcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnql
ggiqimhnngvthctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptk
tpydprwmlagrphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvave
trtvelsipadpanldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgf
sggmkdmydqvlkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemya
dresrgsvlepegtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklk
ereeflipiyhqvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvk
kkihnanpeltdgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqlteedgvhsvie
enikcisrdyvlkqirslvqanpevamdsiihmtqhisptqraeviril

    Sequence, based on observed residues (ATOM records): (download) 
    >4asiA (A:)
dllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplpsdmltytelvld
dqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrigsfgpqedllfl
raselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyrylyltpqdykr
vsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagesslayneiitislv
tcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnqlggiqimhnngv
thctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptktpydprwmlag
rphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvavetrtvelsipad
panldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgfsggmkdmydqv
lkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemyadresrgsvlep
egtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklkereeflipiyh
qvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvkkkihnanpelt
dgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqltvieenikcisrdyvlkqirsl
vqanpevamdsiihmtqhisptqraeviril

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4asiB (B:)
smlintpyvtkdllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplps
dmltytelvlddqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrig
sfgpqedllflraselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyr
ylyltpqdykrvsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagessl
ayneiitislvtcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnql
ggiqimhnngvthctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptk
tpydprwmlagrphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvave
trtvelsipadpanldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgf
sggmkdmydqvlkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemya
dresrgsvlepegtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklk
ereeflipiyhqvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvk
kkihnanpeltdgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqlteedgvhsvie
enikcisrdyvlkqirslvqanpevamdsiihmtqhisptqraeviril

    Sequence, based on observed residues (ATOM records): (download) 
    >4asiB (B:)
dllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplpsdmltytelvld
dqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrigsfgpqedllfl
raselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyrylyltpqdykr
vsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagesslayneiitislv
tcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnqlggiqimhnngv
thctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptktpydprwmlag
rphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvavetrtvelsipad
panldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgfsggmkdmydqv
lkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemyadresrgsvlep
egtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklkereeflipiyh
qvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvkkkihnanpelt
dgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqltsvieenikcisrdyvlkqirs
lvqanpevamdsiihmtq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4asiC (C:)
smlintpyvtkdllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplps
dmltytelvlddqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrig
sfgpqedllflraselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyr
ylyltpqdykrvsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagessl
ayneiitislvtcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnql
ggiqimhnngvthctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptk
tpydprwmlagrphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvave
trtvelsipadpanldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgf
sggmkdmydqvlkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemya
dresrgsvlepegtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklk
ereeflipiyhqvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvk
kkihnanpeltdgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqlteedgvhsvie
enikcisrdyvlkqirslvqanpevamdsiihmtqhisptqraeviril

    Sequence, based on observed residues (ATOM records): (download) 
    >4asiC (C:)
dllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplpsdmltytelvld
dqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrigsfgpqedllfl
raselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyrylyltpqdykr
vsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagesslayneiitislv
tcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnqlggiqimhnngv
thctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptktpydprwmlag
rphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvavetrtvelsipad
panldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgfsggmkdmydqv
lkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemyadresrgsvlep
egtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklkereeflipiyh
qvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvkkkihnanpelt
dgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqltgvhsvieenikcisrdyvlkq
irslvqanpevamdsiihmtqhisptqraeviril

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4asiD (D:)
smlintpyvtkdllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplps
dmltytelvlddqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrig
sfgpqedllflraselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyr
ylyltpqdykrvsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagessl
ayneiitislvtcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnql
ggiqimhnngvthctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptk
tpydprwmlagrphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvave
trtvelsipadpanldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgf
sggmkdmydqvlkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemya
dresrgsvlepegtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklk
ereeflipiyhqvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvk
kkihnanpeltdgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqlteedgvhsvie
enikcisrdyvlkqirslvqanpevamdsiihmtqhisptqraeviril

    Sequence, based on observed residues (ATOM records): (download) 
    >4asiD (D:)
dllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplpsdmltytelvld
dqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrigsfgpqedllfl
raselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyrylyltpqdykr
vsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagesslayneiitislv
tcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnqlggiqimhnngv
thctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptktpydprwmlag
rphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvavetrtvelsipad
panldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgfsggmkdmydqv
lkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemyadresrgsvlep
egtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklkereeflipiyh
qvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvkkkihnanpelt
dgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqltvieenikcisrdyvlkqirsl
vqanpevamdsiihmtqhraeviri

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4asiE (E:)
smlintpyvtkdllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplps
dmltytelvlddqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrig
sfgpqedllflraselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyr
ylyltpqdykrvsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagessl
ayneiitislvtcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnql
ggiqimhnngvthctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptk
tpydprwmlagrphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvave
trtvelsipadpanldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgf
sggmkdmydqvlkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemya
dresrgsvlepegtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklk
ereeflipiyhqvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvk
kkihnanpeltdgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqlteedgvhsvie
enikcisrdyvlkqirslvqanpevamdsiihmtqhisptqraeviril

    Sequence, based on observed residues (ATOM records): (download) 
    >4asiE (E:)
lqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplpsdmltytelvlddq
gqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrigsfgpqedllflra
selaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyrylyltpqdykrvs
alnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagesslayneiitislvtc
raigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnqlggiqimhnngvth
ctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptktpydprwmlagrp
hptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvavetrtvelsipadpa
nldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgfsggmkdmydqvlk
fgayivdglreccqpvlvyippqaelrggswvvidssinprhmemyadresrgsvlepeg
tveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklkereeflipiyhqv
avqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvkkkihnanpeltdg
qiqamlrrwfvevegtvkayvwdnnkdlaewlekqlsvieenikcisrdyvlkqirslvq
a

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4asiF (F:)
smlintpyvtkdllqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplps
dmltytelvlddqgqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrig
sfgpqedllflraselaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyr
ylyltpqdykrvsalnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagessl
ayneiitislvtcraigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnql
ggiqimhnngvthctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptk
tpydprwmlagrphptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvave
trtvelsipadpanldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgf
sggmkdmydqvlkfgayivdglreccqpvlvyippqaelrggswvvidssinprhmemya
dresrgsvlepegtveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklk
ereeflipiyhqvavqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvk
kkihnanpeltdgqiqamlrrwfvevegtvkayvwdnnkdlaewlekqlteedgvhsvie
enikcisrdyvlkqirslvqanpevamdsiihmtqhisptqraeviril

    Sequence, based on observed residues (ATOM records): (download) 
    >4asiF (F:)
lqskrfqaqslgttyiydipemfrqsliklwesmstqaflpspplpsdmltytelvlddq
gqlvhmnrlpggneigmvawkmtfkspeypegrdiivigndityrigsfgpqedllflra
selaraegipriyvsansgariglaeeirhmfhvawvdpedpykgyrylyltpqdykrvs
alnsvhcehvedegesrykitdiigkeegigpenlrgsgmiagesslayneiitislvtc
raigigaylvrlgqrtiqvenshliltgagalnkvlgrevytsnnqlggiqimhnngvth
ctvcddfegvftvlhwlsympksvhssvpllnskdpidriiefvptktpydprwmlagrp
hptqkgqwlsgffdygsfseimqpwaqtvvvgrarlggipvgvvavetrtvelsipadpa
nldseakiiqqagqvwfpdsafktyqaikdfnreglplmvfanwrgfsggmkdmydqvlk
fgayivdglreccqpvlvyippqaelrggswvvidssinprhmemyadresrgsvlepeg
tveikfrrkdlvktmrrvdpvyihlaerlgtpelstaerkelenklkereeflipiyhqv
avqfadlhdtpgrmqekgvisdildwktsrtffywrlrrllledlvkkkihnanpeltdg
qiqamlrrwfvevegtvkayvwdnnkdlaewlekqlieenikcisrdyvlkqirslvq