PDB entry 4ak8

View 4ak8 on RCSB PDB site
Description: Structure of F241L mutant of langerin carbohydrate recognition domain.
Class: sugar binding protein
Keywords: sugar binding protein, langerhans cells, dc-sign, hiv, birbeck granules
Deposited on 2012-02-22, released 2013-04-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-04-03, with a file datestamp of 2013-03-29.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.17754
AEROSPACI score: 0.68 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • engineered mutation (67)
      • variant (104)
    Domains in SCOPe 2.03: d4ak8a_
  • Chain 'B':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • engineered mutation (67)
      • variant (104)
    Domains in SCOPe 2.03: d4ak8b_
  • Chain 'C':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71
      • engineered mutation (67)
      • variant (104)
    Domains in SCOPe 2.03: d4ak8c_
  • Chain 'D':
    Compound: C-type lectin domain family 4 member K
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UJ71 (Start-154)
      • engineered mutation (67)
      • variant (104)
    Domains in SCOPe 2.03: d4ak8d_
  • Heterogens: CA, MG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ak8A (A:)
mwshpqfekiegrmqndilqvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsv
tseseqellyktaggliywigltkagmegdwswvddtpfnkvqsarfwipgepnnagnne
hcgnikapslqawndapcdktflfickrpyvpsep

    Sequence, based on observed residues (ATOM records): (download) 
    >4ak8A (A:)
sqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqellyktaggliywigl
tkagmegdwswvddtpfnkvqsarfwipgepnnagnnehcgnikapslqawndapcdktf
lfickrpyvp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ak8B (B:)
mwshpqfekiegrmqndilqvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsv
tseseqellyktaggliywigltkagmegdwswvddtpfnkvqsarfwipgepnnagnne
hcgnikapslqawndapcdktflfickrpyvpsep

    Sequence, based on observed residues (ATOM records): (download) 
    >4ak8B (B:)
gwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqellyktaggliywigltk
agmegdwswvddtpfnkvqsarfwipgepnnagnnehcgnikapslqawndapcdktflf
ickrpyvp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4ak8C (C:)
mwshpqfekiegrmqndilqvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsv
tseseqellyktaggliywigltkagmegdwswvddtpfnkvqsarfwipgepnnagnne
hcgnikapslqawndapcdktflfickrpyvpsep

    Sequence, based on observed residues (ATOM records): (download) 
    >4ak8C (C:)
sqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqellyktaggliywigl
tkagmegdwswvddtpfnkvqsarfwipgepnnagnnehcgnikapslqawndapcdktf
lfickrpyvp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4ak8D (D:)
mwshpqfekiegrmqndilqvvsqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsv
tseseqellyktaggliywigltkagmegdwswvddtpfnkvqsarfwipgepnnagnne
hcgnikapslqawndapcdktflfickrpyvpsep

    Sequence, based on observed residues (ATOM records): (download) 
    >4ak8D (D:)
sqgwkyfkgnfyyfslipktwysaeqfcvsrnshltsvtseseqellyktaggliywigl
tkagmegdwswvddtpfnkvqsarfwipgepnnagnnehcgnikapslqawndapcdktf
lfickrpyvpsep