PDB entry 4aen

View 4aen on RCSB PDB site
Description: HLA-DR1 with covalently linked CLIP106-120 in reversed orientation
Class: immune system
Keywords: immune system, self antigen, invariant chain, clip
Deposited on 2012-01-11, released 2012-08-01
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-10-10, with a file datestamp of 2012-10-05.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.1853
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4aena1, d4aena2
  • Chain 'B':
    Compound: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4aenb1, d4aenb2
  • Chain 'C':
    Compound: HLA class II histocompatibility antigen gamma chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4aenA (A:)
    ggggsggggsggggsikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrl
    eefgrfasfeaqgalaniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvl
    icfidkftppvvnvtwlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrv
    ehwgldepllkhwefdapsplpetten
    

    Sequence, based on observed residues (ATOM records): (download)
    >4aenA (A:)
    eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
    iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
    rngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4aenB (B:)
    mgdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdae
    ywnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsv
    sgfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehps
    vtspltvewrarsesaqsk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4aenB (B:)
    trprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaeywn
    sqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsknllvcsvsgfypgsiev
    rwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsvtspltvewr
    a
    

  • Chain 'C':
    No sequence available.