PDB entry 4acg

View 4acg on RCSB PDB site
Description: GSK3b in complex with inhibitor
Class: transferase
Keywords: transferase
Deposited on 2011-12-15, released 2012-05-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-11-21, with a file datestamp of 2012-11-16.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.1767
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4acga_
  • Chain 'B':
    Compound: Glycogen synthase kinase-3 beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4acgb_
  • Heterogens: 6LQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4acgA (A:)
msyyhhhhhhdydipttenlyfqgamgsshhhhhhssglvprgshmsgrprttsfaesck
pvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqakl
cdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyv
petvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtav
lklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqp
ifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaia
lcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplat
ilipphariqaaastptnataasdantgdrgqtnnaasasasnst

    Sequence, based on observed residues (ATOM records): (download) 
    >4acgA (A:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlp
viyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnv
syicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlg
tptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltplea
cahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphariq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4acgB (B:)
msyyhhhhhhdydipttenlyfqgamgsshhhhhhssglvprgshmsgrprttsfaesck
pvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqakl
cdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffyssgekkdevylnlvldyv
petvyrvarhysrakqtlpviyvklymyqlfrslayihsfgichrdikpqnllldpdtav
lklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssidvwsagcvlaelllgqp
ifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqikahpwtkvfrprtppeaia
lcsrlleytptarltpleacahsffdelrdpnvklpngrdtpalfnfttqelssnpplat
ilipphariqaaastptnataasdantgdrgqtnnaasasasnst

    Sequence, based on observed residues (ATOM records): (download) 
    >4acgB (B:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlp
viyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnv
syicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlg
tptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltplea
cahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphariq