PDB entry 4a9u
View 4a9u on RCSB PDB site
Description: crystal structure of human chk2 in complex with benzimidazole carboxamide inhibitor
Class: transferase
Keywords: transferase
Deposited on
2011-11-28, released
2012-10-10
The last revision prior to the SCOPe 2.06 freeze date was dated
2012-11-07, with a file datestamp of
2012-11-02.
Experiment type: XRAY
Resolution: 2.48 Å
R-factor: 0.1854
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: serine/threonine-protein kinase chk2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4a9ua1, d4a9ua2 - Heterogens: NO3, EDO, A9U, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4a9uA (A:)
gplgshmsvypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsar
eadpalnveteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkea
tcklyfyqmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmr
tlcgtptylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqits
gkynfipevwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllsee
nestalpqvlaqpstsrkrpregeaegae
Sequence, based on observed residues (ATOM records): (download)
>4a9uA (A:)
msvypkalrdeyimsktlgsevklaferktckkvaikiiskdpalnveteieilkklnhp
ciikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengi
ihrdlkpenvllssqeedclikitdfghskiltslmrtlcgtptylapevlvsvgtagyn
ravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlvkk
llvvdpkarftteealrhpwlqdedmkrkfqdllseenestalpqvla