PDB entry 4a4x

View 4a4x on RCSB PDB site
Description: NEK2-EDE bound to CCT248662
Class: transferase
Keywords: transferase, protein kinase, mitosis
Deposited on 2011-10-20, released 2012-04-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-04-25, with a file datestamp of 2012-04-20.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.2065
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase nek2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51955 (Start-270)
      • expression tag (271-278)
    Domains in SCOPe 2.06: d4a4xa1, d4a4xa2
  • Heterogens: JUP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4a4xA (A:)
mpsraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllr
elkhpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtql
tlalkechrrsdgghtvlhrdlkpanvfldgkqnvklgdfglarilnhdedfakefvgtp
yymspeqmnrmsyneksdiwslgcllyelcalmppftafsqkelagkiregkfrripyry
sdelneiitrmlnlkdyhrpsveeilenplilehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4a4xA (A:)
sraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllrel
khpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtqltl
alkechrrshrdlkpanvfldgkqnvklgdfglvgtpyymspeqmnrneksdiwslgcll
yelcalmppftafsqkelagkiregkfrripyrysdelneiitrmlnlkdyhrpsveeil
enplilehhhhhh