PDB entry 3zz7

View 3zz7 on RCSB PDB site
Description: Crystal structure of 3C protease of coxsackievirus B3 complexed with alpha, beta-unsaturated ethyl ester inhibitor 81
Class: hydrolase
Keywords: hydrolase, picornaviridae, beta-unsaturated ethyl ester inhibitor
Deposited on 2011-08-31, released 2012-09-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C proteinase
    Species: Human coxsackievirus [TaxId:12072]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q90092 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d3zz7a1, d3zz7a2
  • Heterogens: G81, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zz7A (A:)
mgpafefavammkrnsstvkteygeftmlgiydrwavlprhakpgptilmndqevgvlda
kelvdkdgtnleltllklnrnekfrdirgflakeevevneavlaintskfpnmyipvgqv
teygflnlggtptkrmlmynfptragqcggvlmstgkvlgihvggnghqgfsaallkhyf
ndeq

    Sequence, based on observed residues (ATOM records): (download) 
    >3zz7A (A:)
mgpafefavammkrnsstvkteygeftmlgiydrwavlprhakpgptilmndqevgvlda
kelvdkdgtnleltllklnrnekfrdirgflakeevevneavlaintskfpnmyipvgqv
teygflnlggtptkrmlmynfptragqcggvlmstgkvlgihvggnghqgfsaallkhyf
n