PDB entry 3zuk

View 3zuk on RCSB PDB site
Description: crystal structure of mycobacterium tuberculosis zinc metalloprotease zmp1 in complex with inhibitor
Class: hydrolase/inhibitor
Keywords: hydrolase-inhibitor complex, pathogenicity, phagosome maturation
Deposited on 2011-07-19, released 2011-08-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-09-21, with a file datestamp of 2011-09-16.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.17661
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: endopeptidase, peptidase family m13
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zuka_
  • Chain 'B':
    Compound: endopeptidase, peptidase family m13
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3zukb_
  • Heterogens: ZN, RDF, 211, PEG, PGE, PG4, ACT, SO4, CL, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3zukA (A:)
mrgshhhhhhgmasmtggqqmgrdlyddddkdhpftmtlaipsgidlshidadarpqddl
fghvngrwlaeheipadratdgafrslfdraetqvrdliiqasqagaavgtdaqrigdly
asfldeeaveragvqplhdelatidsaadatelaaalgtlqragvgggigvyvdtdskds
trylvhftqsgiglpdesyyrdeqhaavlaaypghiarmfglvyggesrdhaktadriva
letkladahwdvvkrrdadlgynlrtfaqlqtegagfdwvswvtalgsapdamtelvvrq
pdylvtfaslwasvnvedwkcwarwrlirarapwltralvaedfefygrtltgaqqlrdr
wkrgvslvenlmgdavgklyvqrhfppdaksridtlvdnlqeayrisiseldwmtpqtrq
ralaklnkftakvgypikwrdysklaidrddlygnvqrgyavnhdrelaklfgpvdrdew
fmtpqtvnayynpgmneivfpaailqppffdpqadeaanyggigavigheighgfddqga
kydgdgnlvdwwtdddrtefaartkalieqyhaytprdlvdhpgpphvqgaftigenigd
lgglsiallayqlslngnpapvidgltgmqrvffgwaqiwrtksraaeairrlavdphsp
pefrcngvvrnvdafyqafdvteddalfldpqrrvriwn

    Sequence, based on observed residues (ATOM records): (download) 
    >3zukA (A:)
aipsgidlshidadarpqddlfghvngrwlaeheipadratdgafrslfdraetqvrdli
iqasqagaavgtdaqrigdlyasfldeeaveragvqplhdelatidsaadatelaaalgt
lqragvgggigvyvdtdskdstrylvhftqsgiglpdesyyrdeqhaavlaaypghiarm
fglvyggesrdhaktadrivaletkladahwdvvkrrdadlgynlrtfaqlqtegagfdw
vswvtalgsapdamtelvvrqpdylvtfaslwasvnvedwkcwarwrlirarapwltral
vaedfefygrtltgaqqlrdrwkrgvslvenlmgdavgklyvqrhfaksridtlvdnlqe
ayrisiseldwmtpqtrqralaklnkftakvgypikwrdysklaidrddlygnvqrgyav
nhdrelaklfgpvdrdewfmtpqtvnayynpgmneivfpaailqppffdpqadeaanygg
igavigheighgfddqgakydgdgnlvdwwtdddrtefaartkalieqyhaytprdlvdh
pgpphvqgaftigenigdlgglsiallayqlslngnpapvidgltgmqrvffgwaqiwrt
ksraaeairrlavdphsppefrcngvvrnvdafyqafdvteddalfldpqrrvriwn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3zukB (B:)
mrgshhhhhhgmasmtggqqmgrdlyddddkdhpftmtlaipsgidlshidadarpqddl
fghvngrwlaeheipadratdgafrslfdraetqvrdliiqasqagaavgtdaqrigdly
asfldeeaveragvqplhdelatidsaadatelaaalgtlqragvgggigvyvdtdskds
trylvhftqsgiglpdesyyrdeqhaavlaaypghiarmfglvyggesrdhaktadriva
letkladahwdvvkrrdadlgynlrtfaqlqtegagfdwvswvtalgsapdamtelvvrq
pdylvtfaslwasvnvedwkcwarwrlirarapwltralvaedfefygrtltgaqqlrdr
wkrgvslvenlmgdavgklyvqrhfppdaksridtlvdnlqeayrisiseldwmtpqtrq
ralaklnkftakvgypikwrdysklaidrddlygnvqrgyavnhdrelaklfgpvdrdew
fmtpqtvnayynpgmneivfpaailqppffdpqadeaanyggigavigheighgfddqga
kydgdgnlvdwwtdddrtefaartkalieqyhaytprdlvdhpgpphvqgaftigenigd
lgglsiallayqlslngnpapvidgltgmqrvffgwaqiwrtksraaeairrlavdphsp
pefrcngvvrnvdafyqafdvteddalfldpqrrvriwn

    Sequence, based on observed residues (ATOM records): (download) 
    >3zukB (B:)
aipsgidlshidadarpqddlfghvngrwlaeheipadratdgafrslfdraetqvrdli
iqasqagaavgtdaqrigdlyasfldeeaveragvqplhdelatidsaadatelaaalgt
lqragvgggigvyvdtdskdstrylvhftqsgiglpdesyyrdeqhaavlaaypghiarm
fglvyggesrdhaktadrivaletkladahwdvvkrrdadlgynlrtfaqlqtegagfdw
vswvtalgsapdamtelvvrqpdylvtfaslwasvnvedwkcwarwrlirarapwltral
vaedfefygrtltgaqqlrdrwkrgvslvenlmgdavgklyvqrhfaksridtlvdnlqe
ayrisiseldwmtpqtrqralaklnkftakvgypikwrdysklaidrddlygnvqrgyav
nhdrelaklfgpvdrdewfmtpqtvnayynpgmneivfpaailqppffdpqadeaanygg
igavigheighgfddqgakydgdgnlvdwwtdddrtefaartkalieqyhaytprdlvdh
pgpphvqgaftigenigdlgglsiallayqlslngnpapvidgltgmqrvffgwaqiwrt
ksraaeairrlavdphsppefrcngvvrnvdafyqafdvteddalfldpqrrvriwn