PDB entry 3ztx
View 3ztx on RCSB PDB site
Description: Aurora kinase selective inhibitors identified using a Taxol-induced checkpoint sensitivity screen.
Class: transferase/cell cycle
Keywords: transferase-cell cycle complex, transferase, taxol-induced checkpoint inhibitor
Deposited on
2011-07-12, released
2012-02-01
The last revision prior to the SCOPe 2.02 freeze date was dated
2012-02-01, with a file datestamp of
2012-01-27.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.18775
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: serine/threonine-protein kinase 12-a
Species: XENOPUS LAEVIS [TaxId:8355]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3ztxa_ - Chain 'B':
Compound: serine/threonine-protein kinase 12-a
Species: XENOPUS LAEVIS [TaxId:8355]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3ztxb_ - Chain 'C':
Compound: inner centromere protein a
Species: XENOPUS LAEVIS [TaxId:8355]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: inner centromere protein a
Species: XENOPUS LAEVIS [TaxId:8355]
Database cross-references and differences (RAF-indexed):
- Heterogens: ZTX, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3ztxA (A:)
talaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehq
lrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfm
eeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylp
pemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgsk
dliskllryhppqrlplkgvmehpwvkansrrvlppvyqstqsk
Sequence, based on observed residues (ATOM records): (download)
>3ztxA (A:)
kftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehqlrreieiqs
hlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeeladalhy
cherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylppemiegkth
dekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdliskllry
hppqrlplkgvmehpwvkansrrvlppvyq
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3ztxB (B:)
talaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehq
lrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfm
eeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylp
pemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgsk
dliskllryhppqrlplkgvmehpwvkansrrvlppvyqstqsk
Sequence, based on observed residues (ATOM records): (download)
>3ztxB (B:)
talaempkrkftiddfdigrplgnvylarekqnkfimalkvlfksqlekegvehqlrrei
eiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeelad
alhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylppemie
gkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdlisk
llryhppqrlplkgvmehpwvkansrrvlppvy
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.