PDB entry 3wzy

View 3wzy on RCSB PDB site
Description: S266A mutant 3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 580MPa - complex with IPM and Mg
Class: oxidoreductase
Keywords: 3-isopropylmalate dehydrogenase, ipmdh, high-pressure, diamond-anvil cell, dac, oxidoreductase
Deposited on 2014-10-08, released 2015-10-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-01-13, with a file datestamp of 2016-01-08.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Shewanella oneidensis MR-1 [TaxId:211586]
    Gene: leuB, SO_4235
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8E9N3 (12-374)
      • expression tag (11)
      • engineered mutation (276)
    Domains in SCOPe 2.06: d3wzya1, d3wzya2
  • Heterogens: IPM, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3wzyA (A:)
mrgshhhhhhgssyqiavlagdgigpevmaearkvlkavearfglnieyteydvggiaid
nhgcplpeatlkgceaadailfgsvggpkweklppneqpergallplrghfelfcnlrpa
klhdglehmsplrsdisargfdvlcvreltggiyfgkpkgrqgegeseeafdtmrysrre
isriariafeaargrrkkvtsvdkanvlacsvlwrqvveevavdfpdvelehiyidnatm
qllrrpdefdvmlcsnlfgdilsdeiamltgsmgllasasmnstgfglfepaggsapdia
gkgianpiaqilsaalmlrhslkqeeaasaieravtkalnsgyltgellssdqrhkaktt
vqmgdfiadavkagv

    Sequence, based on observed residues (ATOM records): (download) 
    >3wzyA (A:)
ssyqiavlagdgigpevmaearkvlkavearfglnieyteydvggiaidnhgcplpeatl
kgceaadailfgsvggpkweklppneqpergallplrghfelfcnlrpaklhdglehmsp
lrsdisargfdvlcvreltggiyfgkpkgrqgegeseeafdtmrysrreisriariafea
argrrkkvtsvdkanvlacsvlwrqvveevavdfpdvelehiyidnatmqllrrpdefdv
mlcsnlfgdilsdeiamltgsmgllasasmnstgfglfepaggsapdiagkgianpiaqi
lsaalmlrhslkqeeaasaieravtkalnsgyltgellssdqrhkakttvqmgdfiadav
kagv