PDB entry 3wxg

View 3wxg on RCSB PDB site
Description: Crystal structure of CYLD USP domain (C596A) in complex with Lys63-linked diubiquitin
Class: hydrolase/protein binding
Keywords: ubiquitin protease, HYDROLASE-PROTEIN BINDING complex
Deposited on 2014-07-30, released 2015-02-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uncharacterized protein
    Species: Danio rerio [TaxId:7955]
    Gene: cyld, cylda
    Database cross-references and differences (RAF-indexed):
    • Uniprot E7FEV5 (3-End)
      • expression tag (2)
      • engineered mutation (21)
    • Uniprot E7FEV5
  • Chain 'B':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Gene: UBC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG50 (0-75)
      • engineered mutation (62)
    Domains in SCOPe 2.08: d3wxgb_
  • Chain 'C':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3wxgc_
  • Chain 'D':
    Compound: Uncharacterized protein
    Species: Danio rerio [TaxId:7955]
    Gene: cyld, cylda
    Database cross-references and differences (RAF-indexed):
    • Uniprot E7FEV5 (3-End)
      • expression tag (2)
      • engineered mutation (21)
    • Uniprot E7FEV5
  • Chain 'E':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Gene: UBC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG50 (0-75)
      • engineered mutation (62)
    Domains in SCOPe 2.08: d3wxge_
  • Chain 'F':
    Compound: Ubiquitin
    Species: Mus musculus [TaxId:10090]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3wxgf_

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3wxgB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqrestlhlvlrlrgg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3wxgC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlr

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3wxgE (E:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqrestlhlvlrlrgg

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3wxgF (F:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlr