PDB entry 3w1m
View 3w1m on RCSB PDB site
Description: Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-bromoorotate
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: Rossmann Fold, Oxidoreductase, Dihydroorotate/orotate binding, Cytosol, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on
2012-11-16, released
2013-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-11-20, with a file datestamp of
2013-11-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.145
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Dihydroorotate dehydrogenase (fumarate)
Species: Trypanosoma cruzi [TaxId:353153]
Gene: PyrD
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3w1ma_ - Chain 'B':
Compound: Dihydroorotate dehydrogenase (fumarate)
Species: Trypanosoma cruzi [TaxId:353153]
Gene: PyrD
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3w1mb_ - Heterogens: FMN, NCO, RRO, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3w1mA (A:)
mclklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpeprym
afplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqe
kgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaa
vlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrr
cpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyr
tleefrgrvktie
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3w1mB (B:)
mclklnlldhvfanpfmnaagvlcsteedlrcmtasssgalvsksctsaprdgnpeprym
afplgsinsmglpnlgfdfylkyasdlhdyskkplflsisglsveenvamvrrlapvaqe
kgvllelnlscpnvpgkpqvaydfeamrtylqqvslayglpfgvkmppyfdiahfdtaaa
vlnefplvkfvtcvnsvgnglvidaesesvvikpkqgfgglggkyilptalanvnafyrr
cpdklvfgcggvysgedaflhilagasmvqvgtalqeegpgiftrledelleimarkgyr
tleefrgrvktie