PDB entry 3uzq

View 3uzq on RCSB PDB site
Description: Crystal structure of the dengue virus serotype 1 envelope protein domain III in complex with the variable domains of Mab 4E11
Class: immune system
Keywords: dengue antibody neutralization, IMMUNE SYSTEM
Deposited on 2011-12-07, released 2012-02-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-04-18, with a file datestamp of 2012-04-13.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.177
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: anti-dengue Mab 4E11
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3UZQ
    Domains in SCOPe 2.06: d3uzqa1, d3uzqa2
  • Chain 'B':
    Compound: envelope protein
    Species: Dengue virus 1 [TaxId:11053]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3uzqb_
  • Heterogens: GOL, EDO, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3uzqA (A:)
    evklleqsgaelvkpgasvrlsctasgfnikdtymswvkqrpeqglewigridpangdtk
    ydpkfqgkatitadtssntaylhlssltsgdtavyycsrgwegfaywgqgtlvtvsaggg
    gsggggsggggselvmtqtpaslavslgqratiscrasenvdrygnsfmhwyqqkagqpp
    klliyrasnlesgiparfsgsgsrtdftltinpveaddvatyfcqrsnevpwtfgggtkl
    eikrplehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3uzqA (A:)
    klleqsgaelvkpgasvrlsctasgfnikdtymswvkqrpeqglewigridpangdtkyd
    pkfqgkatitadtssntaylhlssltsgdtavyycsrgwegfaywgqgtlvtvsaggggs
    gglvmtqtpaslavslgqratiscrasenvdrygnsfmhwyqqkagqppklliyrasnle
    sgiparfsgsgsrtdftltinpveaddvatyfcqrsnevpwtfgggtkleikrp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3uzqB (B:)
    mgmsyvmctgsfklekevaetqhgtvlvqvkyegtdapckipfstqdekgvtqngrlita
    npivtdkekpvnieteppfgesyiivgagekalklswfkkgssigklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3uzqB (B:)
    yvmctgsfklekevaetqhgtvlvqvkyegtdapckipfstqdekgvtqngrlitanpiv
    tdkekpvnieteppfgesyiivgagekalklswfk