PDB entry 3uyp

View 3uyp on RCSB PDB site
Description: Crystal structure of the dengue virus serotype 4 envelope protein domain III in complex with the variable domains of Mab 4E11
Class: immune system
Keywords: dengue antibody neutralization, IMMUNE SYSTEM
Deposited on 2011-12-06, released 2012-02-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-04-18, with a file datestamp of 2012-04-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: anti-dengue Mab 4E11
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 3UYP
    Domains in SCOPe 2.07: d3uypa1, d3uypa2
  • Chain 'B':
    Compound: envelope protein
    Species: Dengue virus 4 [TaxId:11070]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3uypb_
  • Heterogens: GOL, SO4, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3uypA (A:)
evklleqsgaelvkpgasvrlsctasgfnikdtymswvkqrpeqglewigridpangdtk
ydpkfqgkatitadtssntaylhlssltsgdtavyycsrgwegfaywgqgtlvtvsaggg
gsggggsggggselvmtqtpaslavslgqratiscrasenvdrygnsfmhwyqqkagqpp
klliyrasnlesgiparfsgsgsrtdftltinpveaddvatyfcqrsnevpwtfgggtkl
eikrplehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3uypA (A:)
vklleqsgaelvkpgasvrlsctasgfnikdtymswvkqrpeqglewigridpangdtky
dpkfqgkatitadtssntaylhlssltsgdtavyycsrgwegfaywgqgtlvtvsavmtq
tpaslavslgqratiscrasenvdrygnsfmhwyqqkagqppklliyrasnlesgiparf
sgsgsrtdftltinpveaddvatyfcqrsnevpwtfgggtkleikr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3uypB (B:)
mgmsytmcsgkfsidkemaetqhgttvvkvkyegagapckvpieirdvnkekvvgriiss
tpfaentnsvtnieleppfgdsyivigvgdsaltlhwfrkgssigklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3uypB (B:)
ytmcsgkfsidkemaetqhgttvvkvkyegagapckvpieirdvnkekvvgriisstpfa
entnsvtnieleppfgdsyivigvgdsaltlhwfrk