PDB entry 3uwl

View 3uwl on RCSB PDB site
Description: Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with 5-formyl tetrahydrofolate
Class: transferase
Keywords: methyltransferase, TRANSFERASE
Deposited on 2011-12-02, released 2012-08-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Enterococcus faecalis [TaxId:1351]
    Gene: EF_1576, thyA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3uwla_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Enterococcus faecalis [TaxId:1351]
    Gene: EF_1576, thyA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3uwlb_
  • Chain 'C':
    Compound: Thymidylate synthase
    Species: Enterococcus faecalis [TaxId:1351]
    Gene: EF_1576, thyA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3uwlc_
  • Chain 'D':
    Compound: Thymidylate synthase
    Species: Enterococcus faecalis [TaxId:1351]
    Gene: EF_1576, thyA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3uwld_
  • Heterogens: SO4, FFO, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3uwlA (A:)
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvksadyqgpdmtdfghrvlqdpafaeqykee
hqkfcdailndaefaekygelgniygaqwrhwetkdgsfidqlanviemiktnpdsrrli
vsawnpedvpsmalppchtmfqfyvnegklscqlyqrsadvflgvpfniasyallthlia
hetglevgefvhtlgdahlyqnhveqmqeqlsrevrsfptlvlnpdkasvfdfdmedikv
egydphptikapiav

    Sequence, based on observed residues (ATOM records): (download) 
    >3uwlA (A:)
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvksadyqgeehqkfcdailndaefaekygel
gniygaqwrhwetkdgsfidqlanviemiktnpdsrrlivsawnpedvpsmalppchtmf
qfyvnegklscqlyqrsadvflgvpfniasyallthliahetglevgefvhtlgdahlyq
nhveqmqeqlsrevrsfptlvlnpdkasvfdfdmedikvegydphptikapi

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3uwlB (B:)
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvksadyqgpdmtdfghrvlqdpafaeqykee
hqkfcdailndaefaekygelgniygaqwrhwetkdgsfidqlanviemiktnpdsrrli
vsawnpedvpsmalppchtmfqfyvnegklscqlyqrsadvflgvpfniasyallthlia
hetglevgefvhtlgdahlyqnhveqmqeqlsrevrsfptlvlnpdkasvfdfdmedikv
egydphptikapiav

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3uwlC (C:)
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvksadyqgpdmtdfghrvlqdpafaeqykee
hqkfcdailndaefaekygelgniygaqwrhwetkdgsfidqlanviemiktnpdsrrli
vsawnpedvpsmalppchtmfqfyvnegklscqlyqrsadvflgvpfniasyallthlia
hetglevgefvhtlgdahlyqnhveqmqeqlsrevrsfptlvlnpdkasvfdfdmedikv
egydphptikapiav

    Sequence, based on observed residues (ATOM records): (download) 
    >3uwlC (C:)
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvkkfcdailndaefaekygelgniygaqwrh
wetkdgsfidqlanviemiktnpdsrrlivsawnpedvpsmalppchtmfqfyvnegkls
cqlyqrsadvflgvpfniasyallthliahetglevgefvhtlgdahlyqnhveqmqeql
srevrsfptlvlnpdkasvfdfdmedikvegydphptikapi

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3uwlD (D:)
meeaylalgkkileeghfkedrtgtgtyslfgyqmrfdlakgfpllttkrvpfgliksel
lwflkgdtniryllernnhiwdewaferyvksadyqgpdmtdfghrvlqdpafaeqykee
hqkfcdailndaefaekygelgniygaqwrhwetkdgsfidqlanviemiktnpdsrrli
vsawnpedvpsmalppchtmfqfyvnegklscqlyqrsadvflgvpfniasyallthlia
hetglevgefvhtlgdahlyqnhveqmqeqlsrevrsfptlvlnpdkasvfdfdmedikv
egydphptikapiav