PDB entry 3unk

View 3unk on RCSB PDB site
Description: CDK2 in complex with inhibitor YL5-083
Class: transferase/transferase inhibitor
Keywords: Protein kinase, allosteric ligand, ANS, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-11-15, released 2012-01-25
The last revision prior to the SCOPe 2.01 freeze date was dated 2012-01-25, with a file datestamp of 2012-01-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.18
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3unka_
  • Heterogens: 0BY, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3unkA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3unkA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkiretegvpstaireisllkelnhpni
    vklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrv
    lhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyysta
    vdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkw
    arqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl