PDB entry 3umr

View 3umr on RCSB PDB site
Description: Crystal structure of the G202D mutant of human G-alpha-i1
Class: signaling protein
Keywords: g-protein, alpha subunit, gtpase, guanine nucleotide, signaling protein
Deposited on 2011-11-14, released 2012-10-24
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-10-24, with a file datestamp of 2012-10-19.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: 0.172
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Guanine nucleotide-binding protein G(i) subunit alpha-1
    Species: Homo sapiens [TaxId:9606]
    Gene: GNAI1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63096 (Start-353)
      • engineered mutation (201)
      • conflict (257)
    Domains in SCOPe 2.03: d3umra1, d3umra2
  • Heterogens: GDP, SO4, CL, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3umrA (A:)
mgctlsaedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheag
yseeeckqykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmt
aelagvikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvk
ttgivethftfkdlhfkmfdvdgqrserkkwihcfegvtaiifcvalsdydlvlaedeem
nrmhesmklfdsicnnkcftdtsiilflnkkdlfeekikksplticypeyagsntyeeaa
ayiqcqfedlnkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

    Sequence, based on observed residues (ATOM records): (download) 
    >3umrA (A:)
edkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagyseeeck
qykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmtaelagvi
krlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvkttgivet
hftfkdlhfkmfdvdfegvtaiifcvalsdydlveemnrmhesmklfdsicnnkcftdts
iilflnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythf
tcatdtknvqfvfdavtdviiknnlkdcglf