PDB entry 3uli

View 3uli on RCSB PDB site
Description: Human Cyclin Dependent Kinase 2 (CDK2) bound to azabenzimidazole derivative
Class: transferase/transferase inhibitor
Keywords: azabenzimidazole derivative, Phosphotransfer, Complex with Cyclin A or Cyclin E, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-11-10, released 2013-08-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-09-04, with a file datestamp of 2013-08-30.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.238
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ulia_
  • Heterogens: 1N3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3uliA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3uliA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldvpstaireisllkelnhpnivk
    lldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlh
    rdlkpqnllintegaikladfglarafgvevvtlwyrapeillgckyystavdiwslgci
    faemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvv
    ppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl