PDB entry 3uip

View 3uip on RCSB PDB site
Description: Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II
Class: Ligase/Isomerase/Protein Binding
Keywords: E3, ligase, SUMO, UBC9, RanBP2, nuclear pore complex, Ligase-Isomerase-Protein Binding complex
Deposited on 2011-11-05, released 2011-12-28
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: 0.194
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: SUMO-conjugating enzyme UBC9
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC9, UBCE9, UBE2I
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3uipa_
  • Chain 'B':
    Compound: Small ubiquitin-related modifier 1
    Species: Homo sapiens [TaxId:9606]
    Gene: OK/SW-cl.43, SMT3C, SMT3H3, SUMO1, UBL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3uipb_
  • Chain 'C':
    Compound: ran gtpase-activating protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KIAA1835, RANGAP1, SD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3uipc_
  • Chain 'D':
    Compound: E3 SUMO-protein ligase RanBP2
    Species: Homo sapiens [TaxId:9606]
    Gene: NUP358, RANBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49792 (2-End)
      • expression tag (1)
      • engineered mutation (13)
      • engineered mutation (15)
      • engineered mutation (18)
      • engineered mutation (20-21)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3uipA (A:)
msgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfkl
rmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqell
nepniqdpaqaeaytiycqnrveyekrvraqakkfaps

    Sequence, based on observed residues (ATOM records): (download) 
    >3uipA (A:)
sgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfklr
mlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqelln
epniqdpaqaeaytiycqnrveyekrvraqakkfaps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3uipB (B:)
egeyiklkvigqdsseihfkvkmtthlkklkesycqrqgvpmnslrflfegqriadnhtp
kelgmeeedvievyqeqtgg

    Sequence, based on observed residues (ATOM records): (download) 
    >3uipB (B:)
eyiklkvigqdsseihfkvkmtthlkklkesycqrqgvpmnslrflfegqriadnhtpke
lgmeeedvievyqeqtgg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3uipC (C:)
sltgepapvlsspppadvstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflkv
ssvfkdeatvrmavqdavdalmqkafnsssfnsntfltrllvhmgllksedkvkaianly
gplmalnhmvqqdyfpkalaplllafvtkpnsalescsfarhsllqtlykv

    Sequence, based on observed residues (ATOM records): (download) 
    >3uipC (C:)
advstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflkvssvfkdeatvrmavq
davdalmqkafnsssfnsntfltrllvhmgllksedkvkaianlygplmalnhmvqqdyf
pkalaplllafvtkpnsalescsfarhsllqtlykv

  • Chain 'D':
    No sequence available.