PDB entry 3u8z

View 3u8z on RCSB PDB site
Description: human merlin FERM domain
Class: signaling protein
Keywords: neurofibromatosis, tumor suppressor, SIGNALING PROTEIN
Deposited on 2011-10-17, released 2011-11-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-11-30, with a file datestamp of 2011-11-25.
Experiment type: XRAY
Resolution: 2.64 Å
R-factor: 0.202
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: merlin
    Species: Homo sapiens [TaxId:9606]
    Gene: NF2, SCH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3u8za1, d3u8za2
  • Chain 'B':
    Compound: merlin
    Species: Homo sapiens [TaxId:9606]
    Gene: NF2, SCH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3u8zb1, d3u8zb2
  • Chain 'C':
    Compound: merlin
    Species: Homo sapiens [TaxId:9606]
    Gene: NF2, SCH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3u8zc1, d3u8zc2, d3u8zc3
  • Chain 'D':
    Compound: merlin
    Species: Homo sapiens [TaxId:9606]
    Gene: NF2, SCH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3u8zd1, d3u8zd2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3u8zA (A:)
gplgsqpktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtv
awlkmdkkvldhdvskeepvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiy
cppeasvllasyavqakygdydpsvhkrgflaqeellpkrvinlyqmtpemweeritawy
aehrgrardeaemeylkiaqdlemygvnyfairnkkgtelllgvdalglhiydpenrltp
kisfpwneirnisysdkeftikpldkkidvfkfnssklrvnklilqlcignhdlfmrrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3u8zA (A:)
ktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtvawlkmdk
kvlpvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiycppeasvllasyavq
akygdqmtpemweeritawyaehrgrardeaemeylkiaqdlemygvnyfairnkkgtel
llgvdalglhiydpenrltpkisfpwneirnisysdkeftikpldkkidvfkfnssklrv
nklilqlcignhdlfmrrrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3u8zB (B:)
gplgsqpktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtv
awlkmdkkvldhdvskeepvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiy
cppeasvllasyavqakygdydpsvhkrgflaqeellpkrvinlyqmtpemweeritawy
aehrgrardeaemeylkiaqdlemygvnyfairnkkgtelllgvdalglhiydpenrltp
kisfpwneirnisysdkeftikpldkkidvfkfnssklrvnklilqlcignhdlfmrrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3u8zB (B:)
ktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtvawlkmdk
kvlpvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiycppeasvllasyavq
akygdqmtpemweeritawyaehrgrardeaemeylkiaqdlemygvnyfairnkkgtel
llgvdalglhiydpenrltpkisfpwneirnisysdkeftikpldkkidvfkfnssklrv
nklilqlcignhdlfmrrrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3u8zC (C:)
gplgsqpktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtv
awlkmdkkvldhdvskeepvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiy
cppeasvllasyavqakygdydpsvhkrgflaqeellpkrvinlyqmtpemweeritawy
aehrgrardeaemeylkiaqdlemygvnyfairnkkgtelllgvdalglhiydpenrltp
kisfpwneirnisysdkeftikpldkkidvfkfnssklrvnklilqlcignhdlfmrrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3u8zC (C:)
ktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtvawlkmdk
kvlpvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiycppeasvllasyavq
akygdydpsvhqmtpemweeritawyaehrgrardeaemeylkiaqdlemygvnyfairn
kkgtelllgvdalglhiydpenrltpkisfpwneirnisysdkeftikpldkkidvfkfn
ssklrvnklilqlcignhdlfmrrrk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3u8zD (D:)
gplgsqpktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtv
awlkmdkkvldhdvskeepvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiy
cppeasvllasyavqakygdydpsvhkrgflaqeellpkrvinlyqmtpemweeritawy
aehrgrardeaemeylkiaqdlemygvnyfairnkkgtelllgvdalglhiydpenrltp
kisfpwneirnisysdkeftikpldkkidvfkfnssklrvnklilqlcignhdlfmrrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3u8zD (D:)
ktftvrivtmdaemefncemkwkgkdlfdlvcrtlglretwffglqytikdtvawlkmdk
kvlpvtfhflakfypenaeeelvqeitqhlfflqvkkqildekiycppeasvllasyavq
akyardeaemeylkiaqdlemygvnyfairnkkgtelllgvdalglhiydpenrltpkis
fpwneirnisysdkeftikpldkkidvfkfnssklrvnklilqlcignhdlfmrrrk