PDB entry 3u8h
View 3u8h on RCSB PDB site
Description: Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Class: hydrolase
Keywords: secreted phospholipase A2, phospholipase A2 activity, HYDROLASE
Deposited on
2011-10-17, released
2012-10-17
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-06-12, with a file datestamp of
2013-06-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.194
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Phospholipase A2, membrane associated
Species: Homo sapiens [TaxId:9606]
Gene: PLA2G2A, PLA2B, PLA2L, RASF-A
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3u8ha_ - Chain 'B':
Compound: Phospholipase A2, membrane associated
Species: Homo sapiens [TaxId:9606]
Gene: PLA2G2A, PLA2B, PLA2L, RASF-A
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3u8hb_ - Heterogens: BHP, CA, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>3u8hA (A:)
nlvnfhrmiklttgkeaalsygfygchcgvggrgspkdatdrccvthdccykrlekrgcg
tkflsykfsnsgsritcakqdscrsqlcecdkaaatcfarnkttynkkyqyysnkhcrgs
tprc
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3u8hB (B:)
nlvnfhrmiklttgkeaalsygfygchcgvggrgspkdatdrccvthdccykrlekrgcg
tkflsykfsnsgsritcakqdscrsqlcecdkaaatcfarnkttynkkyqyysnkhcrgs
tprc