PDB entry 3u10

View 3u10 on RCSB PDB site
Description: Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Class: transport protein
Keywords: transport protein
Deposited on 2011-09-29, released 2011-10-26
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-10-26, with a file datestamp of 2011-10-21.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.204
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HCN2, BCNG2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3u10a_
  • Heterogens: CMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3u10A (A:)
qgpsspmdssrrqyqekykqveqymsfhklpadfrqkihdyyehryqgkmfdedsilgel
ngplreeivnfncrklvasmplfanadpnfvtamltklkfevfqpgdyiiregtigkkmy
fiqhgvvsvltkgnkemklsdgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevl
eeypmmrrafetvaidrldrigkknsillh

    Sequence, based on observed residues (ATOM records): (download) 
    >3u10A (A:)
dssrrqyqekykqveqymsfhklpadfrqkihdyyehryqgkmfdedsilgelngplree
ivnfncrklvasmplfanadpnfvtamltklkfevfqpgdyiiregtigkkmyfiqhgvv
svltkgnkemklsdgsyfgeiclltrgrrtasvradtycrlyslsvdnfnevleeypmmr
rafetvaidrldrigkknsill