PDB entry 3tw8

View 3tw8 on RCSB PDB site
Description: GEF domain of DENND 1B in complex with Rab GTPase Rab35
Class: protein transport
Keywords: longin domain, Rab GTPase, guanine exchange factor, PROTEIN TRANSPORT
Deposited on 2011-09-21, released 2011-11-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-11-30, with a file datestamp of 2011-11-25.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.23
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DENN domain-containing protein 1B
    Species: Homo sapiens [TaxId:9606]
    Gene: DENND1B, C1orf218, FAM31B
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Ras-related protein Rab-35
    Species: Homo sapiens [TaxId:9606]
    Gene: RAB35, RAB1C, RAY
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tw8b_
  • Chain 'C':
    Compound: DENN domain-containing protein 1B
    Species: Homo sapiens [TaxId:9606]
    Gene: DENND1B, C1orf218, FAM31B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6P3S1-2 (1-End)
      • expression tag (0)
  • Chain 'D':
    Compound: Ras-related protein Rab-35
    Species: Homo sapiens [TaxId:9606]
    Gene: RAB35, RAB1C, RAY
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tw8d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3tw8B (B:)
smardydhlfklliigdsgvgksslllrfadntfsgsyittigvdfkirtveingekvkl
qiwdtagqerfrtitstyyrgthgvivvydvtsaesfvnvkrwlheinqncddvcrilvg
nknddperkvvetedaykfagqmgiqlfetsakenvnveemfncitelvlrakkdnlakq
q

    Sequence, based on observed residues (ATOM records): (download) 
    >3tw8B (B:)
ydhlfklliigdsgvgksslllrfadntsyittigvdfkirtveingekvklqiwdtagq
erfrtitstyyrgthgvivvydvtsaesfvnvkrwlheinqncddvcrilvgnknddper
kvvetedaykfagqmgiqlfetsakenvnveemfncitelvlrakkdnl

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3tw8D (D:)
smardydhlfklliigdsgvgksslllrfadntfsgsyittigvdfkirtveingekvkl
qiwdtagqerfrtitstyyrgthgvivvydvtsaesfvnvkrwlheinqncddvcrilvg
nknddperkvvetedaykfagqmgiqlfetsakenvnveemfncitelvlrakkdnlakq
q

    Sequence, based on observed residues (ATOM records): (download) 
    >3tw8D (D:)
dydhlfklliigdsgvgksslllrfadntfgsyittigvdfkirtveingekvklqiwdt
agqerfrtitstyyrgthgvivvydvtsaesfvnvkrwlheinqncddvcrilvgnkndd
perkvvetedaykfagqmgiqlfetsakenvnveemfncitelvlrakkdnla