PDB entry 3tvc

View 3tvc on RCSB PDB site
Description: Human MMP13 in complex with L-glutamate motif inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: pseudo dipeptides, potent inhibitors, metzincin, Zinc metalloprotease, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-09-20, released 2012-06-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-10-17, with a file datestamp of 2012-10-12.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: 0.165
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3tvca_
  • Heterogens: ZN, CA, E3P, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3tvcA (A:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgded