PDB entry 3tsr

View 3tsr on RCSB PDB site
Description: X-ray structure of mouse ribonuclease inhibitor complexed with mouse ribonuclease 1
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase, hydrolase inhibitor, leucine-rich repeat, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-09-13, released 2012-09-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-08-20, with a file datestamp of 2014-08-15.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.183
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribonuclease pancreatic
    Species: Mus musculus [TaxId:10090]
    Gene: Rib-1, Rib1, Rnase1, Rns1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tsra_
  • Chain 'B':
    Compound: ribonuclease pancreatic
    Species: Mus musculus [TaxId:10090]
    Gene: Rib-1, Rib1, Rnase1, Rns1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tsrb_
  • Chain 'C':
    Compound: ribonuclease pancreatic
    Species: Mus musculus [TaxId:10090]
    Gene: Rib-1, Rib1, Rnase1, Rns1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tsrc_
  • Chain 'D':
    Compound: ribonuclease pancreatic
    Species: Mus musculus [TaxId:10090]
    Gene: Rib-1, Rib1, Rnase1, Rns1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3tsrd_
  • Chain 'E':
    Compound: ribonuclease inhibitor
    Species: Mus musculus [TaxId:10090]
    Gene: Rnh, Rnh1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91VI7 (1-456)
      • expression tag (0)
    Domains in SCOPe 2.06: d3tsre1, d3tsre2
  • Chain 'F':
    Compound: ribonuclease inhibitor
    Species: Mus musculus [TaxId:10090]
    Gene: Rnh, Rnh1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91VI7 (1-456)
      • expression tag (0)
    Domains in SCOPe 2.06: d3tsrf1, d3tsrf2
  • Chain 'G':
    Compound: ribonuclease inhibitor
    Species: Mus musculus [TaxId:10090]
    Gene: Rnh, Rnh1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91VI7 (1-456)
      • expression tag (0)
    Domains in SCOPe 2.06: d3tsrg1, d3tsrg2
  • Chain 'H':
    Compound: ribonuclease inhibitor
    Species: Mus musculus [TaxId:10090]
    Gene: Rnh, Rnh1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91VI7 (1-456)
      • expression tag (0)
    Domains in SCOPe 2.06: d3tsrh1, d3tsrh2
  • Heterogens: EDO, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tsrA (A:)
mresaaqkfqrqhmdpdgssinsptycnqmmkrrdmtngsckpvntfvhepladvqavcs
qenvtcknrksncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvh
fdatv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tsrA (A:)
resaaqkfqrqhmdpdgssinsptycnqmmkrrdmtngsckpvntfvhepladvqavcsq
envtcknrksncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvhf
datv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3tsrB (B:)
mresaaqkfqrqhmdpdgssinsptycnqmmkrrdmtngsckpvntfvhepladvqavcs
qenvtcknrksncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvh
fdatv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tsrB (B:)
esaaqkfqrqhmdpdgssinsptycnqmmkrrdmtngsckpvntfvhepladvqavcsqe
nvtcknrksncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvhfd
atv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3tsrC (C:)
mresaaqkfqrqhmdpdgssinsptycnqmmkrrdmtngsckpvntfvhepladvqavcs
qenvtcknrksncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvh
fdatv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tsrC (C:)
esaaqkfqrqhmdpsptycnqmmkrrdmtngsckpvntfvhepladvqavcsqenvtckn
rksncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvhfdatv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3tsrD (D:)
mresaaqkfqrqhmdpdgssinsptycnqmmkrrdmtngsckpvntfvhepladvqavcs
qenvtcknrksncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvh
fdatv

    Sequence, based on observed residues (ATOM records): (download) 
    >3tsrD (D:)
esaaqkfqrqhmptycnqmmkrrdmtngsckpvntfvhepladvqavcsqenvtcknrks
ncyksssalhitdchlkgnskypncdykttqyqkhiivacegnpyvpvhfdat

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3tsrE (E:)
mmsldiqceqlsdarwtellpliqqyevvrlddcgltevrckdissavqanpaltelslr
tnelgdggvglvlqglqnptckiqklslqncglteagcgilpgmlrslstlrelhlndnp
mgdaglkllceglqdpqcrleklqleycnltatsceplasvlrvkadfkelvlsnndlhe
pgvrilcqglkdsacqleslklencgitaanckdlcdvvaskaslqeldlssnklgnagi
aalcpglllpscklrtlwlwecditaegckdlcrvlrakqslkelslasnelkdegarll
cesllepgcqleslwiktcsltaascpyfcsvltksrsllelqmssnplgdegvqelcka
lsqpdtvlrelwlgdcdvtnsgcsslanvllanrslreldlsnncmggpgvlqlleslkq
psctlqqlvlydiywtneveeqlraleeerpslriis

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3tsrF (F:)
mmsldiqceqlsdarwtellpliqqyevvrlddcgltevrckdissavqanpaltelslr
tnelgdggvglvlqglqnptckiqklslqncglteagcgilpgmlrslstlrelhlndnp
mgdaglkllceglqdpqcrleklqleycnltatsceplasvlrvkadfkelvlsnndlhe
pgvrilcqglkdsacqleslklencgitaanckdlcdvvaskaslqeldlssnklgnagi
aalcpglllpscklrtlwlwecditaegckdlcrvlrakqslkelslasnelkdegarll
cesllepgcqleslwiktcsltaascpyfcsvltksrsllelqmssnplgdegvqelcka
lsqpdtvlrelwlgdcdvtnsgcsslanvllanrslreldlsnncmggpgvlqlleslkq
psctlqqlvlydiywtneveeqlraleeerpslriis

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3tsrG (G:)
mmsldiqceqlsdarwtellpliqqyevvrlddcgltevrckdissavqanpaltelslr
tnelgdggvglvlqglqnptckiqklslqncglteagcgilpgmlrslstlrelhlndnp
mgdaglkllceglqdpqcrleklqleycnltatsceplasvlrvkadfkelvlsnndlhe
pgvrilcqglkdsacqleslklencgitaanckdlcdvvaskaslqeldlssnklgnagi
aalcpglllpscklrtlwlwecditaegckdlcrvlrakqslkelslasnelkdegarll
cesllepgcqleslwiktcsltaascpyfcsvltksrsllelqmssnplgdegvqelcka
lsqpdtvlrelwlgdcdvtnsgcsslanvllanrslreldlsnncmggpgvlqlleslkq
psctlqqlvlydiywtneveeqlraleeerpslriis

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3tsrH (H:)
mmsldiqceqlsdarwtellpliqqyevvrlddcgltevrckdissavqanpaltelslr
tnelgdggvglvlqglqnptckiqklslqncglteagcgilpgmlrslstlrelhlndnp
mgdaglkllceglqdpqcrleklqleycnltatsceplasvlrvkadfkelvlsnndlhe
pgvrilcqglkdsacqleslklencgitaanckdlcdvvaskaslqeldlssnklgnagi
aalcpglllpscklrtlwlwecditaegckdlcrvlrakqslkelslasnelkdegarll
cesllepgcqleslwiktcsltaascpyfcsvltksrsllelqmssnplgdegvqelcka
lsqpdtvlrelwlgdcdvtnsgcsslanvllanrslreldlsnncmggpgvlqlleslkq
psctlqqlvlydiywtneveeqlraleeerpslriis