PDB entry 3tq9

View 3tq9 on RCSB PDB site
Description: Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: dihydrofolate reductase, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2011-09-09, released 2011-11-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-01-20, with a file datestamp of 2016-01-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Coxiella burnetii [TaxId:777]
    Gene: CBU_1993, folA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3tq9a_
  • Heterogens: NDP, MTX

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3tq9A (A:)
    miitliaamdknrligrnnelpwhlpadlahfksitlgkpivmgrrtfdsigkplphrrn
    ivitqqknliiegcdifyslddalsaltkepeviiiggarifkealpkadkmiltiinhs
    fegdvyfpewndkewkitsqikherdeknpypfqflelrrlenlyfqghhhhhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >3tq9A (A:)
    miitliaamdknrligrnnelpwhlpadlahfksitlgkpivmgrrtfdsigkplphrrn
    ivitqqknliiegcdifyslddalsaltkepeviiiggarifkealpkadkmiltiinhs
    fegdvyfpewndkewkitsqikhfqflelrr