PDB entry 3tki
View 3tki on RCSB PDB site
Description: Crystal structure of Chk1 in complex with inhibitor S25
Class: transferase/transferase inhibitor
Keywords: Chk1, Kinase, cell checkpoint, transferase-transferase inhibitor complex
Deposited on
2011-08-26, released
2012-04-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-04-11, with a file datestamp of
2012-04-06.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.188
AEROSPACI score: 0.58
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Serine/threonine-protein kinase Chk1
Species: Homo sapiens [TaxId:9606]
Gene: CHEK1, CHK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3tkia_ - Heterogens: SO4, S25, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3tkiA (A:)
mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicink
mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
llhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsespsgfskhiqsnldf
spvnsasrtpgsgwskehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3tkiA (A:)
avpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmknikkeicinkmlnhenvv
kfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigith
rdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaep
vdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilve
npsaritipdikkdrwynkplkkgakrprvts