PDB entry 3tjk

View 3tjk on RCSB PDB site
Description: Crystal Structure of human peroxiredoxin IV C245A mutant in reduced form
Class: oxidoreductase
Keywords: thioredoxin fold, sulfenylation, endoplasmic reticulum, OXIDOREDUCTASE
Deposited on 2011-08-24, released 2011-10-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-12-14, with a file datestamp of 2011-12-09.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: 0.162
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxiredoxin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13162
      • engineered mutation (227)
    Domains in SCOPe 2.08: d3tjka_
  • Chain 'B':
    Compound: Peroxiredoxin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13162
      • engineered mutation (227)
    Domains in SCOPe 2.08: d3tjkb_
  • Chain 'C':
    Compound: Peroxiredoxin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13162
      • engineered mutation (227)
    Domains in SCOPe 2.08: d3tjkc_
  • Chain 'D':
    Compound: Peroxiredoxin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13162
      • engineered mutation (227)
    Domains in SCOPe 2.08: d3tjkd_
  • Chain 'E':
    Compound: Peroxiredoxin-4
    Species: Homo sapiens [TaxId:9606]
    Gene: PRDX4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13162
      • engineered mutation (227)
    Domains in SCOPe 2.08: d3tjke_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tjkA (A:)
mgsshhhhhhsqdplvprgsweteerprtreeechfyaggqvypgeasrvsvadhslhls
kakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgdrlee
frsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyledsgh
tlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgsetii
pdpagklkyfdkln

    Sequence, based on observed residues (ATOM records): (download) 
    >3tjkA (A:)
lhlskakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgd
rleefrsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyle
dsghtlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgs
etiipdpagklkyfd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3tjkB (B:)
mgsshhhhhhsqdplvprgsweteerprtreeechfyaggqvypgeasrvsvadhslhls
kakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgdrlee
frsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyledsgh
tlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgsetii
pdpagklkyfdkln

    Sequence, based on observed residues (ATOM records): (download) 
    >3tjkB (B:)
lhlskakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgd
rleefrsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyle
dsghtlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgs
etiipdpagklkyfd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3tjkC (C:)
mgsshhhhhhsqdplvprgsweteerprtreeechfyaggqvypgeasrvsvadhslhls
kakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgdrlee
frsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyledsgh
tlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgsetii
pdpagklkyfdkln

    Sequence, based on observed residues (ATOM records): (download) 
    >3tjkC (C:)
lhlskakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgd
rleefrsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyle
dsghtlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgs
etiipdpagklkyfd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3tjkD (D:)
mgsshhhhhhsqdplvprgsweteerprtreeechfyaggqvypgeasrvsvadhslhls
kakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgdrlee
frsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyledsgh
tlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgsetii
pdpagklkyfdkln

    Sequence, based on observed residues (ATOM records): (download) 
    >3tjkD (D:)
lhlskakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgd
rleefrsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyle
dsghtlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgs
etiipdpagklkyfd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3tjkE (E:)
mgsshhhhhhsqdplvprgsweteerprtreeechfyaggqvypgeasrvsvadhslhls
kakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgdrlee
frsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyledsgh
tlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgsetii
pdpagklkyfdkln

    Sequence, based on observed residues (ATOM records): (download) 
    >3tjkE (E:)
lhlskakiskpapywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgd
rleefrsintevvacsvdsqfthlawintprrqgglgpiripllsdlthqiskdygvyle
dsghtlrglfiiddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevapagwkpgs
etiipdpagklkyfd