PDB entry 3t8x

View 3t8x on RCSB PDB site
Description: Crystal structure of human CD1b in complex with synthetic antigenic diacylsulfoglycolipid SGL12 and endogenous spacer
Class: immune system
Keywords: endogenous spacer ligand, mycobacterial diacylsulfoglycolipid, MHC, glycoprotein, immune system, Immunoglobulin domain/MHC I, Antigen presentation, glycolipid antigen binding, Glycosylation, Cell membrane
Deposited on 2011-08-02, released 2011-10-26
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-10-26, with a file datestamp of 2011-10-21.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.167
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein cd1b
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1B
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3t8xb_
  • Chain 'C':
    Compound: T-cell surface glycoprotein cd1b
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29016 (Start-279)
      • expression tag (280-281)
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3t8xd_
  • Heterogens: SO4, ACT, T8X, ULI, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3t8xB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3t8xD (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm