PDB entry 3sfu

View 3sfu on RCSB PDB site
Description: crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin
Class: transferase
Keywords: Right handed fold, VIRAL REPLICATION ENZYME, RNA binding, TRANSFERASE
Deposited on 2011-06-14, released 2012-05-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-05-09, with a file datestamp of 2012-05-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.182
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA polymerase
    Species: Murine norovirus 1 [TaxId:223997]
    Gene: RdRp
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3sfua_
  • Chain 'B':
    Compound: RNA polymerase
    Species: Murine norovirus 1 [TaxId:223997]
    Gene: RdRp
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3sfub_
  • Chain 'C':
    Compound: RNA polymerase
    Species: Murine norovirus 1 [TaxId:223997]
    Gene: RdRp
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3sfuc_
  • Heterogens: RBV, SO4, MG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3sfuA (A:)
mlprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslq
qvmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssg
ypyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkik
krllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmd
adytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglps
gcpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytm
alrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkg
pnhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsgiemvvprhrs
vlrwvrfgtmdaetpqersavfvnedaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sfuA (A:)
lprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqq
vmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgy
pyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikk
rllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmda
dytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsg
cpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytma
lrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgp
nhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskemvvprhrsvlrwvrfg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3sfuB (B:)
mlprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslq
qvmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssg
ypyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkik
krllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmd
adytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglps
gcpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytm
alrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkg
pnhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsgiemvvprhrs
vlrwvrfgtmdaetpqersavfvnedaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sfuB (B:)
lprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqq
vmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgy
pyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikk
rllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmda
dytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsg
cpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytma
lrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgp
nhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsgiemvvprhrsv
lrwvrfg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3sfuC (C:)
mlprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslq
qvmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssg
ypyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkik
krllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmd
adytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglps
gcpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytm
alrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkg
pnhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsgiemvvprhrs
vlrwvrfgtmdaetpqersavfvnedaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sfuC (C:)
lprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqq
vmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgy
pyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikk
rllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmda
dytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsg
cpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytma
lrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgp
nhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvsvvprhrsvlrwvrfgt