PDB entry 3s8o
View 3s8o on RCSB PDB site
Description: Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide
Class: signaling protein/antagonist
Keywords: Grb2 SH2 domain, phosphotyrosine-containing tripeptide, SIGNALING PROTEIN-ANTAGONIST complex
Deposited on
2011-05-29, released
2011-11-02
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-12-07, with a file datestamp of
2011-12-02.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.153
AEROSPACI score: 0.54
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Growth factor receptor-bound protein 2
Species: Homo sapiens [TaxId:9606]
Gene: GRB2, ASH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3s8oa_ - Chain 'B':
Compound: pYAc6cN
Database cross-references and differences (RAF-indexed):
- Heterogens: NA, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3s8oA (A:)
iemkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlr
dgagkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqvpqqptyvqahhhhhh
Sequence, based on observed residues (ATOM records): (download)
>3s8oA (A:)
emkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrd
gagkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqv
- Chain 'B':
No sequence available.