PDB entry 3s5j

View 3s5j on RCSB PDB site
Description: 2.0A Crystal structure of human phosphoribosyl pyrophosphate synthetase 1
Class: transferase
Keywords: nucleotide synthesis, TRANSFERASE
Deposited on 2011-05-23, released 2012-05-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-04-22, with a file datestamp of 2015-04-17.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribose-phosphate pyrophosphokinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRPS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3s5ja1, d3s5ja2
  • Chain 'B':
    Compound: Ribose-phosphate pyrophosphokinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRPS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3s5jb1, d3s5jb2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3s5jA (A:)
mpnikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgc
geindnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvag
adhiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvts
iadrlnvdfalihkerkkanevdrmvlvgdvkdrvailvddmadtcgtichaadkllsag
atrvyailthgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeai
rrthngesvsylfshvpllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3s5jA (A:)
nikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgcge
indnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvagad
hiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvtsia
drlnvdfalihkedrmvlvgdvkdrvailvddmadtcgtichaadkllsagatrvyailt
hgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeairrthngesv
sylf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3s5jB (B:)
mpnikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgc
geindnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvag
adhiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvts
iadrlnvdfalihkerkkanevdrmvlvgdvkdrvailvddmadtcgtichaadkllsag
atrvyailthgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeai
rrthngesvsylfshvpllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3s5jB (B:)
nikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgcge
indnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvagad
hiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvtsia
drlnvdfalihkedrmvlvgdvkdrvailvddmadtcgtichaadkllsagatrvyailt
hgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeairrthngesv
sylfshvp