PDB entry 3s35

View 3s35 on RCSB PDB site
Description: Structural basis for the function of two anti-VEGF receptor antibodies
Class: IMMUNE SYSTEM/Transferase
Keywords: antibody, KDR, VEGF receptor, cancer, IMMUNE SYSTEM-Transferase complex
Deposited on 2011-05-17, released 2011-08-24
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-08-24, with a file datestamp of 2011-08-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.206
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'H':
  Compound: 6.64 Fab heavy chain
  Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3S35 (0-216)
• Chain 'L':
  Compound: 6.64 Fab light chain
  Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 3S35 (0-216)
  Domains in SCOPe 2.03: d3s35l1, d3s35l2
• Chain 'X':
  Compound: Vascular endothelial growth factor receptor 2
  Species: Homo sapiens [TaxId:9606]
  Gene: KDR, FLK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35968 (3-End)
    • expression tag (2)
• Heterogens: CA, NAG, HOH

PDB Chain Sequences:

• Chain 'H':
  No sequence available.
  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3s35L (L:)
  divltqspaslavslgqratiscrasesvdsygnsfmhwyqqkpgqppklliyrasnles
  giparfsgsgsrtdftltinpveaddvatyycqqsnedpltfgagtklelkradaaptvs
  ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
  stltltkdeyerhnsytceathktstspivksfnrne
  

  
  
• Chain 'X':
  No sequence available.